Table 1 Patient characteristics

Sociodemographic (at the beginning of the disease)

 Female, n(%)

16,929(55.2)

1052(52.0)

259(53.5)

0.0056

 Male, n(%)

13,751(44.8)

971(48.0)

225(46.5)

0.0049

Age^a, µ

53.7

67.4

62.5

 < 0.0001

Age at the time of diagnosis, µ

-

63.1

60.9

 < 0.0001

BMI (kg/m²), µ/N

27.3/1643^b

29.0/1511^b

29.3/378^b

 < 0.0001

Health Status (during the sample period)

 Number of diagnoses (ICD-Chapter) per practice visit, µ

2.0

2.1

2.8

 < 0.0001

 Number of diagnoses for chronical diseases^c per practice visit, µ

0.8

1.3

2.5

 < 0.0001

 Multimorbid^d, n(%)

5547(18.1)

685(33.9)

192(39.7)

 < 0.0001

Specific comorbidities/other diseases (during the sample period)

 Obesity (E66.0, E66.9), n(%)

2091(6.8)

281(13.9)

47(9.7)

 < 0.0001

 Diabetes mellitus 1 and 2 (E10, E11, E14, R73.0), n(%)

4065(13.2)

530(26.2)

119(24.6)

 < 0.0001

 Cardiovascular disease (I20, I21, I24, I25, I70, I63-I66), n(%)

3554(11.6)

493(24.4)

107(22.1)

 < 0.0001

 Mental and behavioral disorders (F00-F99), n(%)

7275(23.7)

658(32.5)

218(45.0)

 < 0.0001

 others^e, n(%)

3002(9.8)

255(12.6)

63(13.0)

 < 0.0001