Table 2 Implementation outcomes for each component of the Humanwide precision health pilot

Penetration/reach

Overall 42% (21 of 50)

94% (46 of 50)

80% (40 of 50) average of 2+ sessions

72% (36 of 50)

64% (32 of 50)

Acceptability

(satisfaction, agreeable, palatable with it) what is acceptable

Positive: Patients and providers very positive; perceived as relevant to health

Negative: Specialist resources needed to interpret results

Positive: Engaged patients holistically; interested patients reported value and potential to address health disparities

Negative: Not all patients interested

Positive: Driver for patient participation in Humanwide

Negative: Variants of uncertain significance^a

Positive: Helped patients meet health goals; supported strong patient-provider relationships; quicker time to titrate meds

Negative: Data and communication volume create burden for providers

Feasibility

(suitability for everyday use, can be carried out, resources/training/

Staff/self-efficacy)

Positive: Successfully executed

Barriers:

Primary care physicians cannot interpret results; requires specialist;

data integration not standardized in EHR

Positive: Successfully executed

Negative: Availability of resources

Positive:

Successfully executed

Negative: Requires specialist/ additional training to interpret results; data integration not standardized; specialist access limited

Positive:

Integrated into regular patient-provider communication

Negative: Technology challenges – Bluetooth pairing

Sustainability/ Spread: Issues that facilitate or threaten spread/scale

Specialist resources needed to interpret results; insurance coverage/cost

Time (providers and patients) and skills needed (providers and staff)

Specialist resources needed to interpret results; insurance coverage/cost

Patient maintenance of digital health monitoring did not occur