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Table 1 Descriptive characteristic of osteoarthritic patients and General Practitioners and Defined Daily Dose (DDD) during the year preceding the study period

From: A cluster randomized trial to measure the impact on nonsteroidal anti-inflammatory drug and proton pump inhibitor prescribing in Italy of distributing cost-free paracetamol to osteoarthritic patients

 Experimental armControl arm
N (%)N (%)
General Practitioners (GPs)87
Sex
 F1 (12.5)3 (42.9)
 M7 (87.5)4 (57.1)
Number of patients
 Mean7.38.4
 Range(1–20)(4–17)
Patients5859
Sex
 F46 (79.3)49 (83.1)
 M12 (20.7)10 (16.9)
Age
 Mean79.678.5
 Range(65–95)(65–97)
Age classes
 65–7415 (25.9)16 (27.1)
 75–8427 (46.6)30 (50.8)
 85+16 (27.6)13 (22.0)
Prescription during the year before randomization
NSAIDs
 Users27 (46.6)28 (47.5)
 Total DDD in the period2328.71030.6
DDD per patient, median (IQR)40 (20–80)26.5 (13.9–60)
 Average DDD per day6.382.82
DDD per day per patient, median (IQR)0.11 (0.05–0.22)0.07 (0.04–0.16)
Opioids
 Users16 (27.6)22 (37.3)
 Total DDD in the period627.0521.4
DDD per patient, median (IQR)14.5 (4–37.2)8 (4–20)
 Average DDD per day1.721.43
DDD per day per patient, median (IQR)0.04 (0.01–0.10)0.02 (0.01–0.05)
PPIs
 Users28 (48.3)27 (45.8)
 Total DDD in the period4249.03719.3
DDD per patient, median (IQR)119 (28–203)133 (42–182)
Average DDD per day11.6410.19
DDD per day per patient, median (IQR)0.33 (0.08–0.56)0.36 (0.12–0.50)
  1. PPIs Proton Pump Inhibitors, NSAIDs Non-steroidal Anti-Inflammatory Drugs, DDD Defined Daily Dose, IQR interquartile range