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Table 4 The incidence of clinical- and symptoms-related HIV indicator conditions among HIV cases compared to matched controls

From: The need to scale up HIV indicator condition-guided testing for early case-finding: a case-control study in primary care

  Cases (N = 224) Controls (N = 2,193)  
  N % N % OR 95% CI P value
Clinical diagnosis
Gonorrhoea 33 14.7 5 0.2 77.1 27.3 to 300.3 <0.0001
Syphilis 22 9.8 6 0.3 52.0 17.6 to 208.2 <0.0001
Leukocytopenia* 2 0.9 0   24.1 1.9 to ∞* 0.02
Trichomoniasis 2 0.9 1 0 20.0 1.0 to 1,179.9 0.05
Hepatitis B 9 4.0 4 0.2 22.5 6.3 to 100.0 <0.0001
Hepatitis C 3 1.3 2 0.1 15.0 1.7 to 179.6 0.01
Thrombocytopenia 4 1.8 4 0.2 12.0 2.0 to 83.1 <0.01
Lymphogranuloma venereum 1 0.4 1 0 10.0 0.1 to 785.0 0.35
Mononeuritis 1 0.4 1 0 10.0 0.1 to 785.0 0.35
Cervical dysplasia 6 2.7 11 0.5 8.1 2.0 to 34.6 <0.01
Chlamydia 20 8.9 28 1.3 8.5 4.2 to 17.0 <0.0001
Genital herpes 8 3.6 7 0.3 10.2 3.1 to 33.7 0.0001
Condyloma acuminata 19 8.5 25 1.1 7.9 4.0 to 15.1 <0.0001
Oral candidiasis 3 1.3 7 0.3 4.5 0.7 to 21.3 0.11
Mononucleosis-like illness 3 1.3 6 0.3 4.9 0.8 to 23.1 0.09
Pneumonia 25 11.2 79 3.6 3.6 2.1 to 5.9 <0.0001
Herpes zoster 10 4.5 32 1.5 3.2 1.4 to 6.9 <0.01
Chronic renal impairment* 0 0 3 0.1 2.6 0 to 24.2 1.00
Hepatitis A* 0 0 4 0.2 1.9 0 to 15.1 1.00
Psoriasis 6 2.7 34 1.6 1.8 0.6 to 4.5 0.30
Seborrhoeic dermatitis 7 3.1 60 2.7 1.2 0.4 to 2.8 0.83
Symptoms
Weight loss 7 3.1 19 0.9 3.9 1.3 to 10.1 0.01
Lymphadenopathy 9 4.0 31 1.4 3.2 1.3 to 7.3 0.01
Fever 8 3.6 29 1.3 2.8 1.1 to 6.3 0.03
Diarrhoea 18 8.0 79 3.6 2.5 1.4 to 4.4 <0.01
Peripheral neuropathy 5 2.2 25 1.1 0.7 0.1 to 2.8 0.95
  1. OR estimated with ‘Median Unbiased Estimate’ displayed with an asterisk (*). ∞ = infinity
  2. Statistical significance indicated in bold