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Table 1 Extraordinary potential of primary care research

From: Leaders, leadership and future primary care clinical research

Innovative and pragmatic study designs and topics Examples
Ground breaking observational research Discovering the infective nature incubation period of Hepatitis A [31]
"Stable" prospective cohort studies Screening for Hypertension [32]
"Stable" retrospective cohort studies Natural history of Hypertension[33]
Large cross-sectional databases Developing a cardiovascular risk assessment tool that is more relevant for the UK population [34]
"Pragmatic" Cluster randomised controlled trials Secondary prevention of CHD [35]
"Pragmatic" systematic reviews Effect of guidelines on clinical practice [36] ; Usage of computers in consultations [37]; Role of antibiotics in sore throat [38]
"Pragmatic" factorial design Laboratory test reminders [39]
Primary qualitative research Chronic care models in primary care [40]; Experience of acute illness [41]
Secondary qualitative research: meta-synthesis Perception of family history in chronic disease [42]; diabetes and diabetes care [43]
Robust economic evaluation alongside trials Hospital at home [44]; Endoscopy for dyspepsia [45]
Process evaluation of randomised trials and complex interventions Self management of inflammatory bowel disease [46]; Integrated heart care [47]
Complexity theory in understanding chronic illness Lived experience of diabetes in the community [48]
Guideline evaluation & implementation; translational research Trial of asthma guidelines [49]; Critical features of the implementation of clinical guidelines [50]
Tackling inequalities Tuberculosis screening [51]
Evaluating primary prevention Exercise program in primary care [52]
Early intervention in the natural history of medical conditions Bell's palsy [53]; Conjunctivitis [54]