Table 1 Baseline characteristics of mildly depressed patients with type 2 diabetes who entered treatment.
Placebo (n = 20) | Paroxetine (n = 23) | |||
|---|---|---|---|---|
Mean | SD | Mean | SD | |
Sex (M/F) | 16/4 | 17/6 | ||
Age (years) | 59.5 | 6.0 | 59.2 | 5.4 |
Body mass index (kg/m2) | 32.0 | 5.3 | 31.7 | 5.5 |
Metabolic parameters | ||||
GHbA1c (%) | 8.7 | 1.3 | 8.5 | 0.9 |
Fasting serum glucose (mmol/l) | 10.4 | 3.4 | 10.4 | 3.7 |
Serum C-Peptide (nmol/l) | 0.69 | 0.53 | 0.74 | 0.91 |
Sex hormone binding globulin (nmol/l) | 43.2 | 23.1 | 37.0 | 18.7 |
Mental status | ||||
Hospital Anxiety and Depression Scale total score | 15.7 | 5.5 | 14.0 | 5.2 |
Hospital Anxiety and Depression Scale depression score | 8.4 | 3.4 | 7.3 | 3.4 |
Hospital Anxiety and Depression Scale anxiety score | 7.3 | 3.0 | 6.7 | 2.6 |
SF-36 composite score | 48.5 | 15.7 | 56.2 | 17.4 |