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Table 2 Reasons for withdrawal from the trials

From: Conducting research in individual patients: lessons learnt from two series of N-of-1 trials

Reasons for withdrawal

No. of patients in series A

No. of patients in series B

Perceived lack of efficacy

4

2

Perceived side effects

1

1

Duration of trial period too long

1

-

  1. Series A: NSAIDs or paracetamol for osteoarthritis
  2. Series B: reduction of temazepam for sleep disturbances