Oral vitamin B12therapy in the primary care setting: a qualitative and quantitative study of patient perspectives

BMC Primary Care

Table 2 Patient factors associated with willingness to switch to oral therapy on initial questionnaire.

	No. (%) of subjects		Unadjusted		Adjusted*
Patient factor	Willing to switch n = 63	Not willing to switch n = 23	OR (95% CI)	p-value	OR (95% CI)	p-value
Time to clinic
0–29 minutes	49 (87)	7 (13)	9.34	<0.001	9.29	0.003
30+ minutes	12 (43)	16 (57)	(3.14–27.78)		(2.16–39.97)
Perceived disadvantages of injections
Frequent visits to see MD/nurse
Agree	38 (86)	6 (14)	4.31	0.010	5.41	0.038
Disagree	25 (60)	17 (40)	(1.49–12.42)		(1.10–26.56)
Cost to health care system
Agree	26 (93)	2 (7)	7.38	0.010	16.68	0.023
Disagree	37 (64)	21 (36)	(1.59–34.23)		(1.51–184.22)

* Adjusted for patient factors at least weakly associated (i.e., p < 0.20) with a willingness to switch to oral B₁₂ therapy in bivariate analyses: gender, time to clinic, satisfaction with past B₁₂ injections, perceived disadvantages of injections (shots are painful, frequent visits to see MD/nurse, cost to health care system), perceived disadvantage of pills (won't see MD/nurse as often)

ISSN: 2731-4553