Outcome variable | Time | Group A | Group B | ||
---|---|---|---|---|---|
Adjusted means (95% CI) and changes in adjusted means (95% CI) | P values | Adjusted means (95% CI) and changes in adjusted means (95% CI) | P values | ||
Overall Diet Score (on the original scale of 25 to75) | V1 | 50.9 ( 48.1 to 53.8) | 48.4 (45. 3 to 51.4) | ||
V2 | 62.9 (60.6 to 65.1) | 53.0 (49.6 to 56.4) | |||
V3 | 65.2 (60.6 to 66.9) | 66.1 (64.0 to 68.2) | |||
V2 vs.V1 | 11.99 (9.2 to 14.7) | P < 0.001 | 4.7 (2.4 to 6.9) | P < 0.001 | |
V3 vs.V2 | 2 (0.1 to 4.4) | P < 0.001 | 13.1 (9.5 to 16.7) | P < 0.001 | |
V3 vs.V1 | 14.2 (11.1 to 17.4) | P = 0.038 | 17.8 (14.4 to 21.1) | P < 0.001 | |
Overall Diet Score (on the modified scale of 100 to 300) | |||||
V1 | 203 (191–215) | 193 (180 to 206) | |||
V2 | 253 (244–263) | 215 (201 to 230) | |||
V3 | 265 (258–272) | 270 (262 to 278) | |||
V2 vs.V1 | 50.3 (38.4 to 62.2) | P < 0.001 | 22.3 (12.9 to 31.7) | P < 0.001 | |
V3 vs.V2 | 11.8 (3.5 to 20.0) | P = 0.007 | 55.0 (40.0 to 70.1) | P < 0.001 | |
V3 vs.V1 | 62.1 (50.1 to 74.1 | P < 0.001 | 77.3 (63.5 -91.2) | P < 0.001 | |
BMI (kg/m2) | |||||
V1 | 30.4 (28.4 to 32.4) | 31.2 (28.4 to 34.1) | |||
V2 | 29.9 (27.9 to 31.9) | 31.1 928.4 to33.90 | |||
V3 | 29.8 (27.7 to 31.8) | 30.3 (27.7 to 33.0) | |||
V2 vs.V1 | −0.5 (−0.1 to −0.8) | P = 0.01 | −0.1 (−0.4 to 0.2) | P = 0.55 | |
V3 vs.V2 | −0.2 (−.1.1 to 0.1) | P = 0.12 | −0.8 (−0.4 to −1.2) | P = 0.001 | |
V3 vs.V1 | −0.6 (−0.2 to −1.1) | P = 0.006 | −0.9 (−0.4 to −1.4) | P < 0.001 | |
LDL-Particles (Number) | V1 | 2048.3 (1861.8 to 2234.8) | 2032.3 (1838.4 to 226.3) | ||
V2 | 1837.5 (1575.3 to 1999.7) | 2114.6 (1941.9 to 2287.2) | |||
V3 | 1772.7 (1597.5 to1947.8) | 1912.7 (1752.5 to 2072.8) | |||
V2 vs.V1 | −210.8 (−371.50 to −50.0) | P = 0.012 | 82.2 (−65.0 to 229.5) | P = 0.26 | |
V3 vs.V2 | −64.8 (−180.4 to 50.7) | P = 0.26 | −201.9 (−315.4 to −88.5) | P = 0.001 | |
V3 vs.V1 | −275.6 ( −411.8 to −139.4) | P < 0.001 | −119.7 (−241.3 to 1.9) | P = 0.053 | |
LDL-Cholesterol (mmol/L) | |||||
V1 | 3.28 (2.96 to 3.60) | 3.44 (3.26 to 3.61) | |||
V2 | 3.14 (2.90 to 3.38) | 3.56 (3.26 to 3.75) | |||
V3 | 2.96 (2.67 to 3.25) | 3.44 (3.14 to 3.73) | |||
V2 vs.V1 | −0.14 (−0.43 to 0.15) | P = 0.38 | 0.12 (−0.04 to 0.29) | P = 0.14 | |
V3 vs.V2 | −0.18 (−0.01 to −0.36) | P = 0.046 | −0.12 (−0.38 to 0.14) | P = 0.40 | |
V3 vs.V1 | −0.32 (−0.06 to −0.58) | P = 0.016 | 0.001 (−0.27 to 0.28) | P = 0.90 | |
HDL-Cholesterol (mmol/L) | |||||
V1 | 1.36 (1.26 to 1.45) | 1.46 (1.36 to 1.56) | |||
V2 | 1.42 (1.30 to 1.54) | 1.46 (1.36 to 1.55) | |||
V3 | 1.38 (1.27 to 1.49) | 1.44 (1.34 to 1.53) | |||
V2 vs.V1 | 0.06 (−0.02 to 0.15) | P = 0.14 | −0.01 (−0.06 to 0.05) | P = 0.82 | |
V3 vs.V2 | −0.04 (−0.03 to 0.05) | P = 0.28 | −0.02 (−0.08 to 0.05) | P = 0.54 | |
V3 vs.V2 | 0.02 (−0.03 to 0.08) | P = 0.37 | −0.03 (−0.10 to 0.05) | P = 0.47 | |
Triglycerides (mmol/L) | |||||
V1 | 2.06 (1.58 to 2.54) | 2.06 (1.68 to 2.44) | |||
V2 | 1.68 (1.41 to 1.95) | 1.95 (1.53 to 2.37) | |||
V3 | 1.85 (1.51 to 2.19) | 1.65 (1.26 to 2.03) | |||
V2 vs.V1 | −0.38 (0.76 to 0.16) | P = 0.055 | −0.11 (−0.27 to 0.05) | P = 0.16 | |
V3 vs.V2 | 0.17 (−0.16 to 0.50) | P = 0.30 | −0.30 (−0.63 to 0.02) | P = 0.07 | |
V3 vs.V1 | −0.21 (−0.65 to 0.24) | P = 0.34 | −0.41 (−0.76 to −0.06) | P = 0.03 | |
Total Cholesterol (mmol/L) | |||||
V1 | 5.60 (5.34 to 5.85) | 5.78 (5.58 to 5.97) | |||
V2 | 5.35 (5.06 to 5.66) | 5.87 (5.64 to 6.10) | |||
V3 | 5.15 (4.83 to 5.46) | 5.60 (5.27 to 5.92) | |||
V2 vs.V1 | −0.24 (−0.49.1 to 0.01) | P = 0.06 | 0.10 (−0.09 to 0.28) | P = 0.30 | |
V3 vs.V2 | −0.21 (−0.44 to 0.02) | P = 0.07 | −0.27(−0.52 to −0.03) | P = 0.03 | |
V3 vs.V1 | −0.45 (−0.65 to −0.25 | P = 0.001 | −0.18 (−0.49 to 0.15) | P = 0.25 | |
Framingham risk score (%) | |||||
V1 | 9.2 (7.0 to 11.4) | 8.4 (7.0 to 9.8) | |||
V2 | 8.3 (6.3 to10.3) | 7.8 (6.5 to 9.1) | |||
V3 | 6.9 (5.1 to 8.7) | 7.1 (6.0 to8.2) | |||
V2 vs.V1 | −0.9 (−1.5 to-0.3) | P = 0.005 | −0.6 (−1.5to 0.3) | P = 0.19 | |
V3 vs.V2 | −1.4 (−2.5 to −0.2) | P = 0.03 | −0.7 (−1.2 to −0.2 | P = 0.014 | |
V3 vs.V1 | −2.3 (−3.6 to −0.9) | P = 0.002 | --1.3 (−2.1 to −0.5) | P = 0.003 |