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Table 2 Baseline characteristics of study participants

From: Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial

  Oral B12 (N = 26) Placebo (N = 24)
Gender (Female) 14 (53.8%) 13 (54.2%)
n (%)   
Age   
Mean (SD) 69.6 yrs (SD = 18.8) 68.6 yrs (SD = 18.5)
Median (range) 76 yrs (31 - 91) 75 yrs (18 - 88)
Serum B12   
Mean (SD) 164 pM/l (SD = 24) 154 pM/l (SD = 20)
Median (range) 164 pM/l (127 - 203) 150 pM/l (126 - 191)
Serum MMA   
Mean (SD) 0.43 μmol/l (SD = 0.25)* 0.41 μmol/l (SD = 0.24)*
Median (range) 0.32 μmol/l (0.19 - 1.1) 0.31 μmol/l (0.15 - 0.92)
MMA ≥ 0.26 μmol/l   
n (%) 18 (83.3%)* 16 (72.7%)*
Serum HCys   
Mean (SD) 18.3 μmol/l (SD = 6.6)* 15.0 μmol/l (SD = 5.3)*
Median (range) 18.1 μmol/l (9.8 - 31.5) 14.3 μmol/l (7.5 - 27.1)
Hematocrit   
Mean (SD) 40.3% (SD = 4.2) 39.5% (SD = 4.6)
Median (range) 39.5% (32 - 46) 40% (27 - 47)
Mean corpuscular volume   
Mean (SD) 91.2 fl (SD = 9.2) 92.6 fl (SD = 5.1)
Median (range) 90 fl (63 - 100) 92 fl (81 - 111)
Serum creatinine   
Mean (SD) 96.4 μmol/l (SD = 27.9) 89.0 μmol/l (SD = 27.2)
Median (range) 86 μmol/l (60 - 160) 89 μmol/l (37 - 137)
Serum folic acid   
Mean (SD) 16.6 nmol/l (SD = 9.1) 19.2 nmol/l (SD = 10.9)
Median (range) 16.2 nmol/l (5.6 - 45.3) 14 nmol/l (5.4 - 33)
  1. Hcys = homocysteine, MMA = methylmalonic acid, SD = standard deviation
  2. * Transport inconvenient generated missing total at random data; samples were not analysed for 2 patients in the oral B12 group and for 2 patients in the placebo group.
  3. One physician did not report results from the blood formula onto the case report form. Data were unvailable for one patient in the oral B12 group.