Table 3 Risk of bias assessment for the studies included in the NICE guideline and for the studies included in the current study
From: Anti-hypertensive drugs deprescribing: an updated systematic review of clinical trials
Study | Random sequence generation | Allocation concealment | Blinding participants and personnel | Blinding of outcome assessment | Incomplete outcome data | Selective data reporting |
|---|---|---|---|---|---|---|
NICE Guidelines | ||||||
Freis, 1975 [18] | ? | – | + | ? | + | – |
Greenberg, 1986 [19] | + | ? | ? | ? | – | ? |
Maland, 1983 [20] | ? | ? | + | ? | + | – |
Current study | ||||||
Sheppard, 2020 [21] | + | + | – | – | + | + |
Luymes, 2018 [22] | + | + | – | – | + | + |