Table 5 Study on patients’ profile in the presence or absence of therapeutic inertia (TI) *
Patients characteristics | Without TI (n = 230) | With TI (n = 155) | P-value |
|---|---|---|---|
Sex | 0.604 | ||
Male | 116 | 74 | |
Female | 114 | 81 | |
Age (years) | 69.6 ± 11.8 | 70.6 ± 13.7 | 0.471 |
BMI (kg/m2) | 25.37 ± 4.85 | 25.33 ± 4.53 | 0.603 |
Smoking | 0.543 | ||
Never smoke | 168 | 106 | |
Ex-smoker | 39 | 33 | |
Smoker smoke | 23 | 16 | |
Duration of DM (years) | 9.46 ± 7.5 | 10.2 ± 8.8 | 0.366 |
Haemoglobin A1c (%) | 6.88 ± 1.22 | 6.85 ± 1.11 | 0.811 |
eGFR (ml/min/1.73m2) | 70.1 ± 24.4 | 71.0 ± 24.4 | 0.702 |
Urine ACR level (mg/mmol) | 39.1 ± 72.4 | 31.0 ± 98.8 | 0.356 |
2.5/3.5–30 | 160 (69.6%) | 132 (85.2%) | 0.001 |
30–300 | 66 (28.7%) | 20 (12.9%) | |
> 300 | 4 (1.7%) | 3 (1.9%) | |
Blood pressure (mmhg) | |||
Systolic | 134.6 ± 18.6 | 128.0 ± 13.6 | 0.000 |
Diastolic | 72.5 ± 12.2 | 69.9 ± 10.8 | 0.036 |
Treatment with ACEI/ARB | |||
Nil | 64 (28.8%) | 64 (41.3%) | 0.000 |
On submaximal dose of ACEI/ARB | 46 (20.0%) | 88 (56.8%) | |
On maximal dose of ACEI/ARB | 120 (52.2%) | 3 (1.9%) | |
Co-morbidities: | |||
HT | 220 (95.7%) | 140 (90.3%) | 0.037 |
CVD | |||
IHD | 11 (4.8%) | 9 (5.8%) | 0.657 |
CVA | 30 (13.1%) | 15 (9.7%) | 0.371 |
PVD | 0 (0%) | 1 (0.6%) | 0.403 |
Other diabetic complications | |||
Diabetic retinopathy | 98(42.6%) | 65 (41.9%) | 0.90 |
Diabetic neuropathy | 36 (15.7%) | 21 (13.5%) | 0.569 |
Lipid Profile | |||
TG (mmol/L) | 1.50 ± 1.05 | 1.55 ± 1.18 | 0.654 |
TC (mmol/L) | 4.31 ± 0.9 | 4.23 ± 0.93 | 0.429 |
HDL (mmol/L) | 1.34 ± 0.39 | 1.29 ± 0.37 | 0.203 |
LDL (mmol/L) | 2.29 ± 0.71 | 2.25±0.80 | 0.553 |