BMC Primary Care

Table 3 FIT sensitivities/specificities at various Hb cut offs and modelling data for high-risk polyps

From: Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy

Hb Threshold	Sensitivity	95% CI	Specificity	95% CI	True +	True -	False +	False -	PPV (%)	NPV (%)
4 μg	71.2	60.5–87.2	79.8	59.7–88.1	29	1895	503	11	6	99.2
10 μg	68.9	53.2–81.4	80.2	76.1–83.7	29	1895	468	13	7	99.2
15 μg	66.7	50.9–79.6	83.1	79.2–86.5	29	1895	385	14	7	99.3
20 μg	64.4	48.7–77.7	85.7	81.9–88.7	29	1895	316	16	8	99.1

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ISSN: 2731-4553

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