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Table 5 Results from the mixed-effects linear regression models for primary and secondary outcomes

From: Using a brief web-based 5A intervention to improve weight management in primary care: results of a cluster-randomized controlled trial

Mixed modela
Outcome n Diff (95% CI) p d (95% CI)
Primary Outcomes
 PACIC 5A sum score
  Baseline 113 0.03 (-2.37–2.44) .976   
  FU1 – 6 months after BL 100 2.53 (-4.97–10.03) .509 0.12 (-0.27–0.52)
  FU2 – 12 months after BL 101 2.81 (-2.45–8.08) .295 0.20 (-0.18–0.60)
Secondary Outcomes
 BMI
  Baseline 125 -0.15 (-0.52–0.23) .450   
  FU1 – 6 months after BL 115 -0.62 (-1.43–0.19) .134 -0.29 (-0.65–0.77)
  FU2 – 12 months after BL 109 -0.22 (-1.10–0.65) .617 -0.95 (-0.47–0.28)
 EQ-5D-5L total score
  Baseline 126 0.21 (-0.92–1.33) .717   
  FU1 – 6 months after BL 115 -0.34 (-3.90–3.22) .851 -0.03 (-0.40–0.33)
  FU2 – 12 months after BL 109 1.28 (-2.25–4.82) .476 0.13 (-0.24–0.51)
 Readiness Ruler
  Baseline 127 0.07 (-0.16–0.29) .559   
  FU1 – 6 months after BL 118 -0.61 (-1.19—-0.03)  < .05 -0.39 (-0.75—-0.02)
  FU2 – 12 months after BL 110 -0.26 (-1.07–0.55) .529 -0.11 (-0.49–0.26)
 WBIS
  Baseline 128 0.02 (-0.10–0.15) .699   
  FU1 – 6 months after BL 113 -0.49 (-0.82—-0.15)  < .01 -0.53 (-0.90—-0.15)
  FU2 – 12 months after BL 108 -0.16 (-0.47–0.15) .308 -0.19 (-0.57–0.18)
 PHQ-9 total score
  Baseline 125 -0.12 (-0.56–0.32) .586   
  FU1 – 6 months after BL 113 -0.22 (-1.15–0.71) .646 -0.08 (-0.45–0.28)
  FU2 – 12 months after BL 106 -0.69 (-2.05–0.65) .310 -0.19 (-0.58–0.18)
  1. Diff Adjusted mean outcome differences, i.e., intervention group minus control group, CI Confidence interval, FU1 Follow-up 1, FU2 Follow-up 2, d Effect size: standardized mean difference (Cohen’s d) at follow-up
  2. aMixed-effects linear regression of outcome on treatment group (intervention group vs. control group), time (baseline, FU1, FU2) and interaction between treatment group and time adjusted for baseline score, age, gender, education, marital status and neuroticism