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Fig. 1 | BMC Family Practice

Fig. 1

From: Vitamin D supplementation improves SIRT1, Irisin, and glucose indices in overweight or obese type 2 diabetic patients: a double-blind randomized placebo-controlled clinical trial

Fig. 1

A schematic for the relationship of vitamin D (VD), sirtuin1 (SIRT1), PPAR-gamma coactivator 1-alpha (PGC-1α), insulin resistance (IR), Irisin, and diabetes. (UCP1: Uncoupling Protein 1; FGF21: Fibroblast Growth Factor 21; PPAR-γ: Peroxisome Proliferation Activated Receptor-Gamma; IL-6: Interleukin 6; TNF-α: Tumour Necrosis Factor-Alpha; hs-CRP: high-sensitivity C-Reactive Protein; NF-κB: Nuclear Factor kappa-light-chain-enhancer of activated B cells)

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