Table 3 Diagnostic accuracy of the MM-BM DDx model by deciles. This table showed sensitivity, specificity, and positive likelihood ratio at each decile of model-predicted odds of multiple myeloma from clinical laboratory values

D1

58

1

57

0.016

0.003, 0.027

100.0 (97.3, 100.0)

0 (0, 0.02)

0.06 (0.00, 0.34)

D2

59

2

57

0.037

0.027, 0.046

99.3 (96.0, 100.0)

12.7 (9.7, 16.1)

0.11 (0.01, 0.45)

D3

58

2

56

0.057

0.046, 0.067

97.8 (93.7, 99.5)

25.3 (21.4, 29.6)

0.11 (0.01, 0.46)

D4

59

4

55

0.075

0.067, 0.087

96.3 (91.6, 98.8)

37.8 (33.3, 42.4)

0.24 (0.06, 0.67)

D5

59

3

56

0.104

0.088, 0.118

93.4 (87.8, 96.9)

50.0 (45.3, 54.7)

0.18 (0.04, 0.56)

D6

58

6

52

0.129

0.118, 0.150

91.2 (85.1, 95.4)

62.4 (57.8, 66.9)

0.38 (0.13, 0.92)

D7

59

10

49

0.183

0.152, 0.227

86.8 (79.9, 92.0)

74.0 (69.7, 78.0)

0.68 (0.30, 1.40)

D8

58

18

40

0.356

0.229, 0.526

79.4 (71.6, 85.9)

84.9 (81.2, 88.1)

1.49 (0.78, 2.76)

D9

59

35

24

1.257

0.543, 3.222

66.2 (57.6, 74.1)

93.8 (91.1, 95.8)

4.83 (2.68, 8.77)

D10

59

55

4

14.864

3.330, 3111.405

40.4 (32.1, 49.2)

99.1 (97.7, 99.8)

45.50 (16.26, 174.85)

Total

586

136

450