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Table 2 Univariate and multivariate regression of log(TBQ + 1) with medical, social and psychological factors (patients’ perspective)

From: Factors associated with patients’ and GPs’ assessment of the burden of treatment in multimorbid patients: a cross-sectional study in primary care

Description   Unvariate regressions Multivariate regression
Beta coefficient (95% CI) p-value Beta coefficient (95% CI) p-value VIF*
Patient’s age in years   −0.019 (− 0.022;-0.016) < 0.001 −0.017 (− 0.020;-0.014) < 0.001 1.174
Patient’s gender is male   0.011 (− 0.064;0.085) 0.777    
Location of practice (ref: Urban) Semi-urban/suburban −0.058 (− 0.154;0.038) 0.236    
Rural −0.020 (− 0.148;0.107) 0.758    
Marital status (ref: Single) Married − 0.192 (− 0.319;-0.065) 0.003    
Separated/divorced −0.009 (− 0.155;0.136) 0.902    
Widow −0.362 (− 0.499;-0.225) < 0.001    
Highest level of schooling achieved (ref: Compulsory education) Upper secondary level −0.036 (− 0.134;0.063) 0.480 − 0.023 (− 0.103;0.058) 0.584 1.056
Tertiary level 0.093 (− 0.005;0.191) 0.062 0.115 (0.034;0.196) 0.006 1.056
GP assessment of number of chronic conditions   0.019 (0.005;0.033) 0.006 0.004 (−0.008;0.016) 0.551 1.265
CIRCS   0.200 (0.101;0.299) < 0.001 0.033 (−0.049;0.115) 0.425 1.076
Total number of different pharmacological treatment the patient is currently taking   0.030 (0.019;0.041) < 0.001 0.008 (−0.003;0.018) 0.160 1.471
Use of a pillbox (dispenser)   0.132 (0.058;0.206) < 0.001 0.076 (0.012;0.139) 0.020 1.122
Home-based care (patient report)   0.015 (−0.105;0.135) 0.807    
Total EQ-5D-3 L score   −0.012 (− 0.014;-0.010) < 0.001 − 0.005 (− 0.007;-0.003) < 0.001 1.717
EQ-5D-3 L health scale (VAS, 0–100)   − 0.010 (− 0.012;-0.009) < 0.001 −0.004 (− 0.006;-0.003) < 0.001 1.457
Deprivation score (DipCare)   0.196 (0.159;0.234) < 0.001 0.060 (0.022;0.097) 0.002 1.399
Health literacy score (HLS EU 6)   −0.329 (− 0.412;-0.245) < 0.001 − 0.162 (− 0.237;-0.087) < 0.001 1.167
Hypertension   − 0.118 (− 0.203;-0.034) 0.006    
Cardiovascular risk   −0.022 (− 0.098;0.054) 0.570    
Diabetes   0.099 (0.019;0.178) 0.016 0.107 (0.039;0.174) 0.002 1.098
Obesity   0.067 (−0.014;0.147) 0.105    
Ischemic heart disease   −0.077 (− 0.159;0.004) 0.063    
Depression   0.210 (0.126;0.294) < 0.001    
Knee osteoarthritis   0.011 (−0.075;0.097) 0.802    
General pain   0.177 (0.088;0.266) < 0.001    
Atrial fibrillation   −0.058 (−0.147;0.032) 0.209 0.105 (0.028;0.183) 0.008 1.151
  1. * variance inflation factor to exclude co-linearity