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Table 3 Odds ratio for factors associated with ≥1 prescription of non-insulin diabetes medication inconsistent with guidelines

From: Prescribing of diabetes medications to people with type 2 diabetes and chronic kidney disease: a national cross-sectional study

 

N

At least one prescription of a non-insulin diabetes medication inconsistent with dosing recommendations n (%)

Unadjusted

Adjusted

OR

95% CI

P value

OR

95% CI

P value

Gender

 Males

1792

1090 (60.8)

1.20

(1.05 to 1.37)

0.008

1.14

(0.92 to 1.40)

0.22

 Females (reference group)

1624

915 (56.3)

1

  

1

  

Rurality

    

0.81

  

0.42

 Major cities of Australia (reference group)

1977

1150 (58.2)

1

  

1

  

 Inner regional Australia

955

568 (59.5)

1.05

(0. 88 to 1.24)

 

1.02

(0.81 to 1.29)

 

 Outer regional Australia

406

237 (58.4)

0.99

(0.80 to 1.24)

 

1.01

(0.73 to 1.38)

 

 Remote and very remote Australia

55

35 (63.6)

1.26

(0.73 to 2.17)

 

1.57

(0.77 to 3.24)

 

Indigenous status

 Aboriginal and/or Torres Strait Islander

62

36 (58.1)

0.94

(0.56 to 1.58)

0.83

0.88

(0.44 to 1.74)

0.84

 Not Aboriginal nor Torres Strait Islander

2679

1580 (59.0)

1

  

1

  

Diabetes duration, (years)

2765

 

1.03

(1.02 to 1.04)

< 0.001

1.02

(1.01 to 1.04)

0.04

Insulin use

 Yes

922

593 (64.3)

1.37

(1.19 to 1.59)

< 0.001

1.07

(0.85 to 1.35)

0.58

 No

2494

1412 (56.6)

1

  

1

  

HbA1c %

2755

 

1.22

(1.14 to 1.31)

< 0.001

1.28

(1.15 to 1.41)

< 0.001

Comorbidities

 Hypertension

2794

1644 (58.8)

1.03

(0.86 to 1.24)

0.72

1.09

(0.82 to 1.45)

0.54

 No hypertension

622

361 (58.0)

1

  

1

  

 CHD

955

566 (59.3)

1.04

(0.91 to 1.19)

0.59

1.00

(0.81 to 1.24)

0.97

 No CHD

2461

1439 (58.5)

1

  

1

  

 HF

429

235 (54.8)

0.83

(0.67 to 1.02)

0.08

0.80

(0.59 to 1.09)

0.16

 No HF

2987

1770 (59.3)

1

  

1

  

 Stroke

384

209 (54.4)

0.82

(0.67 to 1.01)

0.06

0.81

(0.59 to 1.11)

0.18

 No stroke

3032

1796 (59.2)

1

  

1

  

 Amputation

28

17 (60.7)

1.07

(0.50 to 2.30)

0.86

1.54

(0.39 to 6.10)

0.54

 No amputation

3388

1988 (58.7)

1

  

1

  

 Impaired vision

128

69 (53.9)

0.83

(0.58 to 1.19)

0.31

0.91

(0.57 to 1.44)

0.68

 No impaired vision

3288

1936 (58.9)

1

  

1

  

 Retinopathy

180

131 (72.8)

1.94

(1.38 to 2.72)

< 0.001

1.91

(1.18 to 3.09)

0.009

 No retinopathy

3236

2303 (71.2)

1

  

1

  
  1. € Odds ratio estimated using univariable and multivariable logistic regression with robust standard errors
  2. Note: percentages may not sum to 100 due to rounding
  3. Abbreviations: CHD coronary heart disease, HF heart failure