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Table 4 Multivariable logistic regression predicting colorectal adenomatous polyps among diabetes mellitus patients only (N = 445)

From: Diabetes mellitus and hyperglycemia control on the risk of colorectal adenomatous polyps: a retrospective cohort study

 

Odds Ratio

95% CI

P value

Lower

Upper

Model 1

Age (ref: ≤50)

 51~ 55

1.82

0.78

4.25

0.164

 56~ 60

1.92

0.82

4.47

0.132

  > 60

2.93

1.26

6.85

0.013

 Sex (ref: Female)

1.46

0.95

2.24

0.084

Ethnicity (ref: Caucasian)

 African American

0.84

0.52

1.36

0.479

 Hispanic

1.25

0.69

2.28

0.463

 Asian

1.36

0.33

5.63

0.673

 Other/unknown

0.78

0.14

4.37

0.776

 Body mass index

1.01

0.98

1.04

0.437

Oral medication exposure (ref: None)

  < 2 years

0.81

0.47

1.39

0.440

  ≥ 2 years

0.91

0.56

1.49

0.716

Model 2

Age (ref: ≤50)

 51~ 55

1.80

0.77

4.18

0.175

 56~ 60

1.88

0.81

4.38

0.145

  > 60

2.91

1.25

6.78

0.013

 Sex (ref: female)

1.44

0.94

2.21

0.093

Ethnicity (ref: Caucasian)

 African American

0.84

0.52

1.36

0.480

 Hispanic

1.24

0.68

2.26

0.477

 Asian

1.27

0.31

5.23

0.738

 Other/unknown

0.75

0.13

4.20

0.741

 Body mass index

1.01

0.98

1.04

0.447

Insulin exposure (ref: None)

  < 2 years

1.01

0.40

2.54

0.978

  ≥ 2 years

1.03

0.53

1.99

0.938

Model 3

Age (ref: ≤50)

 51~ 55

1.85

0.73

4.72

0.196

 56~ 60

2.28

0.90

5.77

0.081

  > 60

3.58

1.42

9.06

0.007

 Sex (ref: female)

1.47

0.94

2.30

0.092

Ethnicity (ref: Caucasian)

 African American

0.82

0.49

1.35

0.432

 Hispanic

1.24

0.67

2.30

0.497

 Asian

1.32

0.32

5.48

0.701

 Other/unknown

0.75

0.13

4.27

0.747

 Body mass index

1.01

0.98

1.04

0.483

Hemoglobin A1c (ref: < 5.7)

 5.7–6.4

0.91

0.28

3.00

0.880

 6.5–7.9

0.99

0.31

3.18

0.992

  ≥ 8.0

1.03

0.30

3.61

0.962

  1. Model 1 is predicting polyps among diabetic patients on oral medication only; model 2 is predicting polyps among diabetic patients on insulin; and model 3 is predicting polyps among diabetic patients with different levels of Hemoglobin A1c level