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Table 2 Evidence summary [17] of cognitive tests for cognitive impairment (dementia and MCI versus normal cognition)

From: How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care

Test Studies (n) Test time (min) Cut-off score Study population, % dementia / % MCI Number of participants analysed Sens (95% CI) Spec (95% CI) PPV (95% CI) NPV (95% CI)
MoCA 1 10 < 26 8/19 107 86 (67, 96) 76 (65, 85) 56 (40, 71) 94 (85, 98)
Mini-Cog 2 3–4 2/3 40/12 371 84 (79, 89) 88 (81, 93) 92 (87, 95) 77 (70, 83)
    2/3 3/39 630 39 (34, 45) 78 (73, 82) 57 (49, 64) 63 (59, 68)
MMSE 3 7–10 23/24 4/26 269 53 (43, 64) 92 (88, 95) 71 (59, 81) 85 (78, 89)
    23/24 9/47 160 77 (67, 85) 70 (58, 80) 77 (67, 85) 70 (56, 80)
    23/24 4/5 1115 72 (62, 81) 89 (65, 99) 39 (32, 47) 97 (96, 98)
  1. Only the studies reporting a cut-off score that was studied more than once are depicted in the table. Abbreviations: CI Confidence Interval, MCI Mild Cognitive Impairment, NR Not Reported, Sens Sensitivity, Spec Specificity, NPV Negative Predictive Value, PPV Positive Predictive Value, AUC Area Under the Curve. Abbreviations cognitive tests: MoCA Montreal Cognitive Assessment, MMSE Mini Mental State Examination