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Table 2 Evidence summary [17] of cognitive tests for cognitive impairment (dementia and MCI versus normal cognition)

From: How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care

Test

Studies (n)

Test time (min)

Cut-off score

Study population, % dementia / % MCI

Number of participants analysed

Sens (95% CI)

Spec (95% CI)

PPV (95% CI)

NPV (95% CI)

MoCA

1

10

< 26

8/19

107

86 (67, 96)

76 (65, 85)

56 (40, 71)

94 (85, 98)

Mini-Cog

2

3–4

2/3

40/12

371

84 (79, 89)

88 (81, 93)

92 (87, 95)

77 (70, 83)

   

2/3

3/39

630

39 (34, 45)

78 (73, 82)

57 (49, 64)

63 (59, 68)

MMSE

3

7–10

23/24

4/26

269

53 (43, 64)

92 (88, 95)

71 (59, 81)

85 (78, 89)

   

23/24

9/47

160

77 (67, 85)

70 (58, 80)

77 (67, 85)

70 (56, 80)

   

23/24

4/5

1115

72 (62, 81)

89 (65, 99)

39 (32, 47)

97 (96, 98)

  1. Only the studies reporting a cut-off score that was studied more than once are depicted in the table. Abbreviations: CI Confidence Interval, MCI Mild Cognitive Impairment, NR Not Reported, Sens Sensitivity, Spec Specificity, NPV Negative Predictive Value, PPV Positive Predictive Value, AUC Area Under the Curve. Abbreviations cognitive tests: MoCA Montreal Cognitive Assessment, MMSE Mini Mental State Examination