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Table 1 Evidence summary [17] of cognitive tests for MCI (MCI versus normal cognition, dementia not included)

From: How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care

Test Studies (n) Test time (min) Cut-off score Study population, % MCI Number of participants analysed Sens (95% CI) Spec (95% CI) PPV (95% CI) NPV (95% CI)
CDT 3 1–3 ≤ 9 48 465 41 (34, 47) 83 (78, 88) 69 (60, 77) 60 (55, 65)
   ≤ 9 15 3198 58 (54, 63) 57 (55, 59) 19 (17, 22) 89 (87, 90)
   ≤ 9 14 428 69 (56, 81) 63 (58, 68) 23 (17, 30) 93 (89, 96)
MMSE 2 7–10 < 28 84 91 47 (36, 59) 73 (45, 92) 90 (76, 97) 22 (11, 35)
   < 28 44 524 45 (39, 52) 80 (75, 84) 64 (56, 71) 66 (60,70)
MoCA 2 10 < 26 24 152 100 (91, 100) 50 (41,59) 39 (29, 50) 100 (94, 100)
   < 26 20 99 80 (56, 94) 76 (65, 85) 46 (29, 63) 94 (85, 98)
  1. Only the studies reporting a cut-off score that was studied more than once are depicted in the table. Abbreviations: CI=Confidence Interval, MCI Mild Cognitive Impairment, NR Not Reported, Sens Sensitivity, Spec Specificity, NPV Negative Predictive Value, PPV Positive Predictive Value, AUC Area Under the Curve. Abbreviations cognitive tests: CDT ClockDrawing Test, MMSE Mini Mental State Examination, MoCA Montreal Cognitive Assessment