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Table 1 Characteristics of women with clinically suspected acute uncomplicated cystitis: External validation cohort and development cohort [8]

From: External validation study of a clinical decision aid to reduce unnecessary antibiotic prescriptions in women with acute cystitis

  Validation Cohort Development Cohort
Characteristic Number Percent Number Percent
Total 397 100.0 331 100.0
Age
  ≤ 50 years old 194 48.9 211 63.8
  > 50 years of age 203 51.1 120 36.3*
Province
 British Columbia 61 15.4 56 16.9
 Alberta 44 11.0 25 7.6
 Saskatchewan 8 2.0 13 3.9
 Manitoba 8 2.0 11 3.3
 Ontario 208 52.4 195 58.9
 Quebec 27 6.8 3 0.9
 New Brunswick 9 2.3 8 2.4
 Nova Scotia 9 2.3 12 3.6
 Prince Edward Island 7 1.8 2 0.6
 Newfoundland 16 4.0 6 1.8
Symptoms
 Dysuria 335 84.4 262 79.2
 Frequency 349 87.9 304 92.1
 Urgency 315 79.4 273 83.2
 History of fever 13 3.3 13 4.0
 Flank pain 69 17.4 83 25.4*
Management
 Would order culture 351 88.4 259 78.7*
 Prescribed antibiotic 381 96.0 292 88.5*
Urine leukocytes (>trace) 316 79.6 243 73.4
Urine nitrites (any) 123 31.0 88 26.6
Positive Urine Culture 245 61.7 208 62.8
  1. *p < 0.01, adjusted for clustering by physician