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Table 2 Rates per patient year (95% CI) and rate ratios (95% CI) of GP consultations, tests, prescriptions and referrals from 10 years before until 10 years after a first recorded diagnosis of CFS/ME in paediatric cases compared with controls

From: Health care resource use by patients before and after a diagnosis of chronic fatigue syndrome (CFS/ME): a clinical practice research datalink study

  Year −10 to −6 Year −5 to −1 Year 0 Year 1 to 5 Year 6 to 10
Total person years
 Cases 2088 3715 916 3290 1076
 Controls 1996 3591 916 3257 1077
GP consultations
 Cases (rate) 3.77 (3.69, 3.85) 4.43 (4.36, 4.49) 8.22 (8.04, 8.41) 4.42 (4.35, 4.49) 4.01 (3.89, 4.13)
 Controls (rate) 2.59 (2.52, 2.66) 1.89 (1.84, 1.93) 2.01 (1.91, 2.10) 2.36 (2.31, 2.42) 2.47 (2.38, 2.57)
 Rate ratio 1.45 (1.40, 1.51) 2.34 (2.28, 2.41) 4.10 (3.90, 4.31) 1.87 (1.82, 1.92) 1.62 (1.54, 1.70)
Diagnostic tests
 Cases (rate) 1.42 (1.37, 1.47) 8.44 (8.35, 8.54) 29.4 (29.1, 29.8) 10.3 (10.2, 10.4) 11.8 (11.6, 12.0)
 Controls (rate) 0.53 (0.49, 0.56) 1.21 (1.17, 1.24) 2.28 (2.19, 2.38) 3.90 (3.83, 3.97) 5.00 (4.87, 5.14)
 Rate ratio 2.70 (2.51, 2.89) 7.01 (6.79, 7.23) 12.9 (12.3, 13.5) 2.64 (2.59, 2.70) 2.37 (2.29, 2.44)
Prescriptions
 Cases (rate) 3.00 (2.93, 3.08) 3.37 (3.31, 3.43) 5.67 (5.52, 5.83) 3.83 (3.77, 3.90) 3.65 (3.54, 3.77)
 Controls (rate) 2.08 (2.02, 2.14) 1.46 (1.42, 1.50) 1.71 (1.62, 1.79) 1.92 (1.88, 1.97) 1.99 (1.91, 2.07)
 Rate ratio 1.44 (1.39, 1.50) 2.31 (2.23, 2.38) 3.33 (3.14, 3.52) 1.99 (1.93, 2.05) 1.84 (1.74, 1.93)
Referrals
 Cases (rate) 0.25 (0.23, 0.27) 0.43 (0.41, 0.45) 1.28 (1.21, 1.35) 0.42 (0.40, 0.44) 0.39 (0.36, 0.43)
 Controls (rate) 0.18 (0.16, 0.20) 0.14 (0.13, 0.15) 0.15 (0.12, 0.17) 0.16 (0.15, 0.17) 0.16 (0.13, 0.18)
 Rate ratio 1.40 (1.22, 1.60) 3.08 (2.79, 3.41) 8.83 (7.38, 10.6) 2.61 (2.36, 2.89) 2.53 (2.12, 3.03)