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Table 3 Crude and adjusted odds ratios (OR) with 95 % confidence intervals (CI) for the association between characteristics of single-handed practices and initiating long-term treatment with PPIs

From: General practice variation when initiating long-term prescribing of proton pump inhibitors: a nationwide cohort study

 

Crude OR (95 % CI)

P-value

Adjusted OR* (95 % CI)

P-value

Patients per GP

 <1350

1

.

1

.

 1350-1575

0.96 (0.84;1.11)

0.60

1.02 (0.88;1.17)

0.81

 1576-1750

0.95 (0.83;1.09)

0.45

1.07 (0.92;1.23)

0.38

 >1750

0.91 (0.80;1.03)

0.13

1.04 (0.91;1.20)

0.53

Practice location

 Capital area

1

.

1

.

 Provincial city

1.08 (0.98;1.19)

0.13

1.06 (0.96;1.17)

0.29

 Rural area

1.18 (1.06;1.31)

<0.001

1.05 (0.94;1.18)

0.37

GP gender

 Male

1

.

1

.

 Female

0.79 (0.72;0.87)

<0.001

0.89 (0.81;0.99)

0.03

GP age group

 Under 45 years

1

.

1

.

 45-49 years

1.02 (0.80;1.30)

0.88

0.95 (0.73;1.22)

0.67

 50-54 years

1.02 (0.82;1.27)

0.83

0.96 (0.77;1.21)

0.74

 55-59 years

1.19 (0.97;1.45)

0.10

1.11 (0.90;1.37)

0.35

 60-64 years

1.39 (1.14;1.71)

<0.001

1.26 (1.02;1.56)

0.03

 65 years or above

1.38 (1.12;1.71)

<0.001

1.29 (1.03;1.62)

0.03

Training practice

 No

1

.

1

.

 Yes

0.96 (0.87;1.07)

0.46

0.96 (0.86;1.07)

0.45

  1. *Estimates adjusted for practice characteristics and patient characteristics in terms of age, gender, specific gastrointestinal morbidity, socioeconomic status (income, educational level, cohabitation status), comedication with non-steroidal anti-inflammatory drugs (NSAIDs), antiplatelet drugs, anticoagulants, selective serotonine reuptake inhibitors (SSRIs) and comorbidity