Open Access

Erratum to: Pneumococcal lower respiratory tract infections in adults: an observational case–control study in primary care in Belgium

  • Johan Flamaing1, 2Email author,
  • Wilfried De Backer3,
  • Yves Van Laethem4,
  • Stéphane Heijmans5 and
  • Annick Mignon6
BMC Family PracticeBMC series – open, inclusive and trusted201617:25

https://doi.org/10.1186/s12875-016-0420-4

Received: 9 February 2016

Accepted: 9 February 2016

Published: 2 March 2016

The original article was published in BMC Family Practice 2015 16:66

Due to a change in reagent affecting the performance of the Urinary Antigen Detection (UAD) assay, the positivity cut-off values of the assay had to be revised. A number of epidemiological studies have been affected by this change, including the original version of this article [1].

All samples of the study have been reanalysed and the impact on the study results can be found in the attached Excel sheet (Additional file 1):
  • Due to change in cut-off for serotype 5 and 14, there is one case of serotype 5 and of serotype 14 less.

  • The revision of the analysis showed 1 additional positive results for serotype 18C and for serotype 23 F

  • Overall the total number of positive UAD results has not changed.

Results of the assay are shown in the corrected Tables 3 and 4, included in this erratum.
Table 3

Cross-table of the results of the BinaxNOW and Urine Antigen Detection assaysa

 

BinaxNOW assay

Total

N(%)

Negative

N(%)

Positive

N(%)

Urine Antigen Detection Assay

Negative N (%)

433 (95.0)

8 (1.7)

441 (96.7)

Positive N (%)

11 (2.4)

4 (0.9)

15 (3.3)

Total N (%)

444 (97.4)

12 (2.6)

456 (100.0)

a88 contaminated samples were eliminated from the analysis

Table 4

Number and proportion of the serotypes in pneumococcal serious lower respiratory tract infections using the Urine Antigen Detection (UAD) assay

Pneumococcal serotype

N

%

1

1

6.67

3

1

6.67

6A

2

13.33

7 F

2

13.33

14

1

6.67

18C

2

13.33

19A

5

33.33

23 F

1

6.67

Totala

15

100.0

a15 (3.3 %) out of 456 SLRTI cases were positive for the UAD assay

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of Geriatric Medicine, University Hospitals of Leuven
(2)
Department of Clinical and Experimental Medicine, KU Leuven
(3)
Department of Pulmonary Medicine, University Hospital and University of Antwerp
(4)
Department of Infectiology, University Hospital Saint-Pierre
(5)
Clinical Research Network, Researchlink
(6)
Medical Affairs, Pfizer Vaccines

Reference

  1. Flamaing J, De Backer W, Van Laethem Y, Heijmans S, Mignon A. Pneumococcal lower respiratory tract infections in adults: an observational case–control study in primary care in Belgium. BMC Fam Pract. 2015;16:66.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© Flamaing et al. 2016

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