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Table 2 Patients at high risk in primary prevention

From: From hypertension control to global cardiovascular risk management: an educational intervention in a cluster-randomised controlled trial

 

Complex intervention A n = 675

Simple intervention B n = 649

A vs. B

 

Mean FU

95% CI

Mean FU

95% CI

Difference/Odds ratio

95% CI

p

ICC

p

CVR

13.0%

12.5%-13.6%

12.5%

11.9%-13.1%

Δ = 0.5%

-0.3%-1.3%

0.197

0.029

0.004

RR systolic [mmHg]

138.0

136.4-139.7

137.3

135.6-139.1

Δ = 0.7

-1.7-3.1

0.563

0.082

<0.001

RR diastolic [mmHg]

80.5

79.6-81.4

80.0

79.0-80.9

Δ = 0.5

-0.8-1.8

0.461

0.078

<0.001

Control rate RR < 140/90

46.7%

40.4%-53.1%

46.9%

40.3%-53.5%

OR = 0.99

0.68-1.45

0.966

0.128

<0.001

Control rate RR < 160/95

86.8%

83.1%-90.6%

88.9%

85.4%-92.3%

OR = 0.82

0.51-1.31

0.405

0.141

<0.001

Cholesterol [mg/dl]

221.9

219.1-224.6

220.9

218.1-223.7

Δ = 1.0

-3.0-4.93

0.634

0.015

0.085

Current smoker

12.0%

9.7%-14.4%

14.4%

11.9%-17.0%

OR = 0.71

0.44-1.16

0.171

0.093

0.019

ASS

21.4%

19.1%-23.7%

23.9%

21.0%-26.8%

OR = 0.67

0.37-1.19

0.172

0.206

<0.001

Statins

23.3%

19.7%-26.9%

19.4%

15.8%-23.0%

OR = 1.52

0.89-2.62

0.128

0.206

<0.001

  1. Outcomes at follow up in subpopulation at high CVR (10-year mortality ≥ 5%), but no manifest CVD (complete cases), adjusted for baseline and taking cluster effects into account by use of a mixed model.