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Table 2 Baseline clinical and biochemical characteristics and their changes (from baseline to follow-up)

From: Decreasing cholesterol levels in the community – lifestyle change with statin?

 

Total cholesterol at baseline

 

p for linearity

 

< 4.9

4.9–5.7

> 5.7

 
 

N = 115

N = 106

N = 105

 

Fasting Plasma cholesterol, mmol/L

    

  Baseline

4.05

5.28

6.58

-

  Change

0.53 (0.36 to 0.71)

-0.29 (-0.43 to -0.14)

-1.23 (-1.46 to -1.01)

0.14*

Body mass index, kg/m2

    

  Baseline

26.2 (5.1)

27.4 (4.4)

28.6 (4.7)

< 0.001

  Change

0.59 (0.23 to 0.94)

0.29 (-0.09 to 0.066)

0.03 (-0.34 to 0.41)

0.42*

Fasting Plasma glucose, mmol/L

    

  Baseline

5.50 (1.14)

5.48 (0.68)

5.47 (0.97)

0.41

  Change

0.57 (0.34 to 0.80)

0.33 (0.09 to 0.57)

0.51 (0.27 to 0.75)

0.86*

Fasting Plasma LDL cholesterol, mmol/L

    

Males

    

  Baseline

2.45 (0.55)

3.58 (0.32)

4.45 (0.64)

< 0.001

  Change

0.11 (-0.08 to 0.30)

-0.58 (-0.75 to -0.40)

-1.34 (-1.63 to -1.07)

0.47*

Females

    

  Baseline

2.35 (0.47)

3.10 (0.45)

4.29 (0.66)

< 0.001

  Change

0.15 (-0.00 to 0.31)

-0.37 (-0.52 to -0.21)

-1.14 (-1.43 to -0.86)

0.21*

Fasting Plasma HDL cholesterol, mmol/L

    

Males

    

  Baseline

1.05 (0.40)

1.14 (0.29)

1.11 (0.35)

0.45

  Change

0.30 (0.22 to 0.37)

0.13 (0.05 to 0.21)

0.16 (0.09 to 0.23)

0.015*

Females

    

  Baseline

1.27 (0.34)

1.45 (0.41)

1.44 (0.52)

0.026

  Change

0.23 (0.15 to 0.31)

0.18 (0.09 to 0.26)

0.17 (0.07 to 0.26)

0.19*

Fasting Plasma triglycerides, mmol/L

    

Males

    

  Baseline

1.12 (0.57)

1.33 (0.67)

1.81 (1.13)

< 0.001

  Change

0.07 (-0.18 to 0.31)

0.05 (-0.20 to 0.29)

-0.09 (-0.31 to 0.14)

0.090*

Females

    

  Baseline

0.88 (0.33)

1.22 (0.60)

1.59 (0.84)

< 0.001

  Change

0.14 (0.02 to 0.25)

-0.12 (-0.24 to -0.01)

-0.30 (-0.43 to -0.17)

0.025*

Blood pressure, mmHg

    

Systolic

    

  Baseline

132 (20)

139 (17)

146 (18)

< 0.001

  Change

6.1 (3.1 to 9.1)

5.7 (2.6 to 8.9)

6.1 (3.0 to 9.2)

0.050*

Diastolic

    

  Baseline

79 (11)

3 (10)

87 (11)

<0.001

  Change

2.2 (0.35 to 4.0)

1.3 (-0.6 to 3.2)

0.5 (-1.4 to 2.4)

0.036*

  1. Baseline values as means (SD), change values as means with 95% CI.
  2. *Adjusted for age, sex and baseline values.