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Table 3 Cox regression analysis of uACR testing within 12 months (2229 events of total n = 12,988)

From: Timeliness in chronic kidney disease and albuminuria identification: a retrospective cohort study

Variable

Category

Univariate

Multivariable*

  

HR

(95%CI)

p

HR

(95%CI)

p

Sex (female vs. male)

1.42

(1.31-1.54)

<0.001

1.09

(1.00-1.19)

0.438

Age (continuous)

0.99

(0.98-0.99)

<0.001

0.99

(0.99-1.00)

0.028

IMD quintile (vs. least deprived)

1 (most deprived)

1.20

(1.03-1.40)

<0.001

0.88

(0.75-1.02)

0.135

2

1.29

(1.13-1.46)

 

1.05

(0.92-1.19)

3

1.13

(1.01-1.27)

 

0.98

(0.87-1.10)

4

0.97

(0,86-1.09)

 

0.91

(0.81-1.02)

Cardiovascular disease at baseline (vs. no CVD)

1.27

(1.16-1.39)

<0.001

0.948

(0.86-1.04)

0.260

Diabetes at baseline(vs. n diabetes)

10.24

(9.41-11.14)

<0.001

9.32

(8.54-10.18)

<0.001

Hypertension at baseline (vs. no hypertension)

1.46

(1.34-1.59)

<0.001

1.06

(0.97-1.16)

0.215

Baseline eGFR (continuous)

1.01

(1.01-1.02)

<0.001

1.01

(1.00-1.01)

0.014

Year of joining cohort (vs. 2007)

2008

1.08

(0.75-1.56)

<0.001

1.24

(0.86-1.79)

<0.001

 

2009

2.09

(1.46-2.99)

 

2.56

(1.78-3.68)

 

2010

2.30

(1.60-3.30)

 

2.65

(1.84-3.82)

 

2011

2.34

(1.63-3.38)

 

2.73

(1.89-3.94)

 

2012

2.65

(1.83-3.83)

 

2.54

(1.75-3.69)

CKD registration within a year (vs. not)

2.94

(2.69, 3.22)

<0.001

2.79

(2.55-3.06)

<0.001

  1. *adjusted for age, sex, index of multiple deprivation, cardiovascular disease, hypertension, diabetes, baseline eGFR, year of joining cohort, CKD registration within 1 year.
  2. Abbreviations in Table 3: CKD chronic kidney disease, IMD Index of multiple deprivation, BP blood pressure, eGFR estimated Glomerular Filtration Rate, CVD cardiovascular disease.