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Table 5 Patient demographics and independent variables, including benzodiazepines and z-hypnotics

From: Patient factors associated with SSRI dose for depression treatment in general practice: a primary care cross sectional study

  n = 1610 Unadjusted odds ratio (95% CI) p-value
Mean Age ± SD (range) years 46 ± 12 (18 to 70) 1.00 (1.00 to 1.01) 0.432
Male (%) 551 (34.2) 1  
Female (%) 1059 (65.8) 1.17 (0.93 to 1.46) 0.186
Deprivation (%)
  SIMD quintile 1 (least deprived) 93 (5.9) 1  
  SIMD quintile 2 153 (9.7) 0.92 (0.50 to 1.70) 0.794
  SIMD quintile 3 90 (5.7) 1.75 (0.90 to 3.43) 0.101
  SIMD quintile 4 264 (16.7) 1.29 (0.73 to 2.28) 0.373
  SIMD quintile 5 (most deprived) 985 (62.1) 1.41 (0.82 to 2.44) 0.213
  SIMD unknown (not in mode) 25 (1.6)   
Co-morbidities (%)
  0 1028 (63.9) 1  
  1 415 (25.8) 1.20 (0.93 to 1.55) 0.152
  ≥2 167 (10.4) 1.12 (0.79 to 1.58) 0.533
Current Smoking Status (%)
  Non-smoker 900 (56.6) 1  
  Smoker 691 (43.4) 1.16 (0.93 to 1.45) 0.192
  Smoking status unknown (not in model) 19 (1.2)   
SSRI use (%)
  ADM for <2 y (%) 1143 (71.0) 1  
  Same ADM for ≥2 y 467 (29.0) 1.94 (1.53 to 2.47) <0.001
Practice (% practice pop.)
  1 82 (5.1) 1  
  3 242 (15.0) 1.48 (0.77 to 2.83) 0.241
  6 201 (12.5) 2.78 (1.49 to 5.18) 0.001
  8 322 (20.0) 1.96 (1.07 to 3.58) 0.029
  9 181 (11.2) 4.17 (2.22 to 7.81) <0.001
  10 302 (18.8) 2.60 (1.42 to 4.78) 0.002
  11 280 (17.4) 3.62 (1.98 to 6.66) <0.001
B&Z use (%)
  None 1420 (88.2) 1  
  Long-term B&Z for ≥8 weeks 190 (11.8) 2.05 (1.47 to 2.86) <0.001
  1. CI: 95% confidence interval. SD: standard deviation. SIMD: Scottish Index of Multiple Deprivation. SSRI: selective serotonin re-uptake inhibitor. ADM: antidepressant medicine.
  2. Co-morbidities: Individuals had one or more of the following: asthma, COPD, cardiovascular disease, stroke, diabetes mellitus and/or hypertension.
  3. B&Z: bzodiazepine and/or z –hypnotic.