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Table 4 Mean daily doses and differences in short-term and long-term (same SSRI ≥2 years) mean doses

From: Patient factors associated with SSRI dose for depression treatment in general practice: a primary care cross sectional study

  ADM <2 years (n = 1909) ADM ≥2 years (n = 753) Difference in mean dose (mg) 95% CI Mann-Whitney U-test All ADMs (n = 2662)
Number of ADMs (%) Mean dose (SD) mg Number of ADMs (%) Mean dose (SD) mg Number of ADMs (%) Mean dose (SD) mg
Citalopram 929 (34.9) 25.8 (12.2) 258 (9.7) 31.2 (14.8) 5.4 (3.6 to 7.2) <0.001 1187 (44.6) 27.0 (13.0)
Fluoxetine 753 (28.3) 27.2 (12.0) 316 (11.9) 30.6 (14.0) 3.4 (1.6 to 5.2) <0.001 1069 (40.2) 28.2 (12.7)
Sertraline 147 (5.5) 91.0 (43.7) 76 (2.9) 106.6 (49.2) 15.6 (2.3 to 28.8) 0.019 223 (8.4) 96.3 (46.1)
Paroxetine 35 (1.3) 28.0 (11.8) 67 (2.5) 29.4 (12.7) 1.4 (-3.6 to 6.4) 0.832 102 (3.8) 28.9 (12.3)
Escitalopram 44 (1.7) 15.2 (5.6) 35 (1.3) 15.4 (6.8) 0.2 (-2.6 to 3.0) 0.94 79 (3.0) 15.3 (6.1)
Fluvoxamine 1 (0.0)   1 (0.0)     2 (0.1)  
Total 1909 (71.7)   753 (28.3)     2662 (100%)  
  1. Note: Total mean dose and difference in doses between short-term and long-term use presented as means and SD to aid clarity of actual differences groups.
  2. ADMs: antidepressant medicines. SD: standard deviation.
  3. : Percentage of total antidepressants prescribed to the 2662 patients.
  4. : Dose distribution for ADM <2 years and ≥2 years compared using Mann-Whitney U-test.