Table 4 Logistic regression models for "moderate/poor" compared to "good/excellent" SRH for chronic conditions and psychosocial measures in EPIC-Norfolk

Age

(N = 11,439)

(N = 13,829)

(N = 25268)

>65 vs 39-64

1.3 (1.2-1.5)

1.5 (1.4-1.6)

1.4 (1.3-1.5)

Social Class

(N = 11,249)

(N = 13,485)

(N = 24734)

Non-manual vs manual

0.5 (0.5-0.6)

0.6 (0.6-0.7)

0.6 (0.5-0.6)

Sex

(N = 25268)

Female vs male

-

-

1.0 (1.0-1.1)

Psychosocial measures

(N = 7619)

(N = 9676)

(N = 17295)

Diagnosis of depression (present vs absent) ^†

1.1 (0.9-1.2)

0.8 (0.8-1.0)

0.9 (0.9-1.0)

Antidepressant use (use vs no use) ^†

3.7 (3.0-4.5)

2.9 (2.6-3.4)

3.2 (2.8-3.5)

SF-36 Mental health (>80 vs. ≤80 ) ^†

3.7 (3.2-4.2)

3.0 (2.7-3.4)

3.3 (3.0-3.6)

SF-36 Role Emotional (=100 vs. ≤99) ^†

3.1 (2.7-3.5)

2.8 (2.5-3.1)

2.9 (2.7-3.1)

SF-36 Social Functioning (=100 vs. ≤99) ^†

4.6 (4.1-5.5)

4.0 (3.5-4.4)

4.2 (3.9-4.6)

Neuroticism scale (<4 vs > =4) ^†

2.5 (2.2-2.8)

2.4 (2.1-2.6)

2.4 (2.2-2.6)

Chronic conditions

(N = 11,439)

(N = 13,829)

(N = 25268)

Cancer^†

1.5 (1.2-1.8)

1.8 (1.6-2.1)

1.7 (1.5-1.9)

Cancer adjusted ^†

1.3 (0.9-1.0)

1.8 (1.4-2.2)

1.6 (1.4-1.9)

Stroke^†

4.5 (3.3-6.0)

2.4 (1.7-3.3)

3.4 (2.7-4.3)

Stroke adjusted ^†

3.1 (2.1-4.7)

1.6 (0.9-2.7)**

2.3 (1.7-3.2)

Heart attack^†

4.1 (3.5-4.9)

3.8 (2.8-5.2)

4.0 (3.4-4.6)

Heart attack adjusted ^†

4.2 (3.3-5.3)

4.3 (2.9-6.5)

4.1 (3.4-5.1)

Diabetes^†

2.9 (2.3-3.6)

2.9 (2.2-3.8)

2.9 (2.4-3.4)

Diabetes adjusted ^†

2.5 (1.9-3.4)

2.5 (1.7-3.7)

2.5 (2.0-3.2)

Arthritis^†

1.2 (1.1-1.3)

1.0 (1.0-1.1)

1.1 (1.0-1.2)

Arthritis adjusted ^†

1.1 (1.0-1.3)**

1.0 (0.8-1.1)**

1.0 (0.9-1.1)**

Respiratory (asthma or bronchitis)^†

0.9 (0.8-1.1)

1.1 (0.9-1.2)

1.0 (0.9-1.1)

Respiratory adjusted ^†

0.9 (0.8-1.1)**

1.2 (1.0-1.3)

1.1 (0.9-1.2)**

Multimorbidity

(N = 11,439)

(N = 13,829)

(N = 25268)

None reported^†

Ref

Ref

Ref

None adjusted ^‡

Ref

Ref

Ref

One^†

1.4 (1.3-1.6)

1.3 (1.2-1.4)

1.3 (1.2-1.4)

One adjusted ^†

1.4 (1.2-1.6)

1.3 (1.1-1.4)

1.3 (1.2-1.4)

Two conditions^†

2.1 (1.8-2.5)

1.5 (1.3-1.8)

1.8 (1.6-2.0)

Two adjusted ^†

1.9 (1.5-2.3)

1.6 (1.3-2.0)

1.7 (1.5-2.0)

Three or more conditions^†

5.8 (3.9-8.5)

2.2 (1.4-3.6)

3.8 (2.8-5.1)

Three adjusted ^†

5.2 (3.0-8.9)

2.1 (1.1-3.9)

3.4 (2.3-5.1)