Inclusion criteria |
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   • aged 6–18 years |
   • history of allergic rhinitis for at least 1 year |
   • IgE antibodies ≥0.7 kU/l to house dust mite |
   • no use of nasal steroids in the month before start of baseline measurements |
   • rhinitis symptom score of at least 4 out of 12 during last 3 months |
   • signed informed consent |
Exclusion criteria |
   • severe asthma (requiring 800 mcg budesonide daily or equivalent for other inhaled steroids; or requiring >3 courses of oral prednisone/prednisolone in previous year or required hospital stay for asthma in previous year) |
   • sensitization to pets present at home (IgE antibodies ≥0.7 kU/l) |
   • planned surgery of nasal cavity |
   • having received immunotherapy in past 3 years |
   • language barrier |
   • contraindications to sublingual immunotherapy (as supplied by the manufacturer) |