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Table 3 Means (and 95% CI:s) of quality of life and mental health rating scores for subjects who completed the study.

From: Quality of life and metabolic status in mildly depressed patients with type 2 diabetes treated with paroxetine: A double-blind randomised placebo controlled 6-month trial

 

Placebo (n = 14)

Paroxetine (n = 23)

Placebo-Paroxetine

 
 

Mean (95% CI)

Mean (95% CI)

Mean difference (95% CI)

p

SF-36

    

   Baseline

51.2 (42.6 to 59.8)

56.2 (48.6 to 63.7)

-4.7 (-16.3 to 6.4)

0.381

   3 months

59.1 (51.2 to 67.0)

70.1 (63.4 to 76.7)

-11.0 (-21.4 to -0.6)

0.039

   6 months

56.9 (47.5 to 66.2)

65.8 (58.5 to 73.6)

-8.9 (-20.8 to 2.9)

0.135

HADS total score

    

   Baseline

15.8 (12.5 to 19.1)

14.0 (11.7 to 16.2)

1.8 (-1.9 to 5.6)

0.327

   3 months

11.2 (9.0 to 13.5)

8.5 (6.6 to 10.4)

2.8 (-0.2 to 5.7)

0.066

   6 months

12.1 (8.9 to 15.4)

10.2 (7.6 to 12.7)

1.9 (-2.2 to 6.1)

0.351

HADS depression score

    

   Baseline

8.2 (6.2 to 10.2)

7.3 (5.8 to 8.7)

0.9 (-1.4 to 3.4)

0.416

   3 months

5.1 (3.8 to 6.3)

3.8 (2.7 to 4.9)

1.3 (-0.4 to 2.9)

0.129

   6 months

6.2 (4.6 to 7.7)

5.5 (4.3 to 6.6)

0.7 (-1.2 to 2.7)

0.448

HADS anxiety score

    

   Baseline

7.6 (5.8 to 9.4)

6.7 (5.6 to 7.8)

0.9 (-1.1 to 2.8)

0.366

   3 months

6.2 (4.8 to 7.6)

4.6 (3.5 to 5.8)

1.6 (-0.2 to 3.4)

0.085

   6 months

6.0 (4.0 to 8.0)

4.7 (3.2 to 6.2)

1.3 (-1.2 to 3.8)

0.312

  1. Mean differences between groups were obtained with analyses of covariance with the baseline value as a covariate. Means at three and six months are estimated marginal means. HADS = Hospital Anxiety and Depression Scale.