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Table 7 Details of Abstracts (duplicates removed)

From: Inhaled ciclesonide versus inhaled budesonide or inhaled beclomethasone or inhaled fluticasone for chronic asthma in adults: a systematic review

Author Date Comparator Study size Reported characterists Duration Outcome Measures
Boulet et al 2003 CIC 400 mcg (mdi) od am Vs. BUD 400 mcg (turbo) od am 359 Randomized double blind multicenter 12 weeks parallel Lung function FEV1 FVC Symptoms Change in symptoms % symptom free days use of rescue meds
Ukena et al 2003 CIC 400 mcg (mdi) od pm Vs. BUD 400 mcg (turbo) od pm 399 Randomized double blind multicenter 12 weeks parallel Lung function FEV1 FVC, Timing of onset of action PEF Symptoms Change in symptoms % symptom free days use of rescue meds HPA Suppression Urine cortisol
Hansel et al 2003 CIC 100 mcg (mdi) od am Vs. CIC 400 mcg (mdi) od am Vs. BUD 200 mcg (turbo) bd 554 Randomized double blind multicenter 12 weeks parallel Lung function FEV1 FVC PEF Symptoms Change in symptoms % symptom free days use of rescue meds HPA Suppression Urine cortisol
Derom et al 2001 CIC 400 mcg od Vs. CIC 800 mcg od Vs. CIC 800 mcg bd Vs. FP 500 mcg bd Vs. FP 1000mcg bd 25 Randomized double blind double dummy placebo controlled 7 days 6 period crossover with at least 3 weeks washout period Airway responsiveness to AMP PC20 FEV1(doubling doses) HPA Suppression Plasma cortisol Urinary cortisol excretion