Inhaled ciclesonide versus inhaled budesonide or inhaled beclomethasone or inhaled fluticasone for chronic asthma in adults: a systematic review

Table 7 Details of Abstracts (duplicates removed)

Author	Date	Comparator	Study size	Reported characterists	Duration	Outcome Measures
Boulet et al	2003	CIC 400 mcg (mdi) od am Vs. BUD 400 mcg (turbo) od am	359	Randomized double blind multicenter	12 weeks parallel	Lung function FEV1 FVC Symptoms Change in symptoms % symptom free days use of rescue meds
Ukena et al	2003	CIC 400 mcg (mdi) od pm Vs. BUD 400 mcg (turbo) od pm	399	Randomized double blind multicenter	12 weeks parallel	Lung function FEV1 FVC, Timing of onset of action PEF Symptoms Change in symptoms % symptom free days use of rescue meds HPA Suppression Urine cortisol
Hansel et al	2003	CIC 100 mcg (mdi) od am Vs. CIC 400 mcg (mdi) od am Vs. BUD 200 mcg (turbo) bd	554	Randomized double blind multicenter	12 weeks parallel	Lung function FEV1 FVC PEF Symptoms Change in symptoms % symptom free days use of rescue meds HPA Suppression Urine cortisol
Derom et al	2001	CIC 400 mcg od Vs. CIC 800 mcg od Vs. CIC 800 mcg bd Vs. FP 500 mcg bd Vs. FP 1000mcg bd	25	Randomized double blind double dummy placebo controlled	7 days 6 period crossover with at least 3 weeks washout period	Airway responsiveness to AMP PC20 FEV1(doubling doses) HPA Suppression Plasma cortisol Urinary cortisol excretion

ISSN: 2731-4553