Kanniess et al
|
2001
|
No. completing
|
15
|
BUD
|
2 weeks crossover
3–8 weeks washout
|
No info about allocation
|
Participant
|
Yes
|
Yes but no evidence of method
|
1 (5.25%)
|
no
|
yes
|
| |
Mean age
|
33
| | | |
Admin.
|
no
| | | | |
| |
Stable
|
yes
| | | |
Observer
|
yes
| | | | |
| |
Non smokers only
|
yes
| | | |
Analyst
|
?
| | | | |
| |
Mean FEV1 % pred:
|
94
| | | | | | | | | |
Nave et al
|
2005
|
No. completing
|
18
|
BUD
|
Combined treatment Oropharyngeal washings taken at 0 mins on day 1, 15 mins on day2, 30 mins on day 3, 45 mins on day 4 and 60 mins on day 5.
|
No info about allocation
|
Participant
|
no
|
Yes but no evidence of method
|
0
|
yes
|
yes
|
| |
Mean age
|
33
| | | |
Admin.
|
no
| | | | |
| |
Stable
|
yes
| | | |
Observer
|
no
| | | | |
| |
Non smokers only
|
no
| | | |
Analyst
|
?
| | | | |
| |
Mean FEV1 % pred:
|
?
| | | | | | | | | |
Lee, Fardon et al
|
2005
|
No. completing
|
14
|
FP
|
4 weeks crossover 2 weeks washout
|
No info about allocation
|
Participant
|
yes
|
Yes but no evidence of method
|
6 (30%)
|
yes
|
yes
|
| |
Mean age
|
47
| | | |
Admin.
|
?
| | | | |
| |
Stable
|
yes
| | | |
Observer
|
?
| | | | |
| |
Non smokers only
|
yes
| | | |
Analyst
|
?
| | | | |
| |
Mean FEV1 % pred:
|
77
| | | | | | | | | |
Lee, Haggart et al
|
2004
|
No. completing
|
19
|
FP
|
4 weeks crossover 2 weeks washout
|
No info about allocation
|
Participant
|
yes
|
Yes but no evidence of method
|
4 (17.5%)
|
yes
|
yes
|
| |
Mean age
|
45
| | | |
Admin.
|
?
| | | | |
| |
Stable
|
yes
| | | |
Observer
|
?
| | | | |
| |
Non smokers only
|
yes
| | | |
Analyst
|
?
| | | | |
| |
Mean FEV1 % pred:
|
90
| | | | | | | | | |
Richter et al
|
2005
|
No. completing
|
18
|
FP
|
Combined treatment Treatement 5–14 days (5 treatments in total at 0, 15, 30, 45 and 60 minutes). Minimum 1 day washout
|
No info about allocation
|
Participant
|
no
|
Yes but no evidence of method
|
0
|
yes
|
yes
|
| |
Mean age
|
37
| | | |
Admin.
|
no
| | | | |
| |
Stable
|
yes
| | | |
Observer
|
no
| | | | |
| |
Non smokers only
|
no
| | | |
Analyst
|
?
| | | | |
| |
Mean FEV1 % pred:
|
91
| | | | | | | | | |