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Table 2 Clinical and Demographic Data of Patient Cohort

From: Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses

   THGI Non Transient p
Demographics No of Patients 17 (53%) 15 (47%) > 0.05
  Males 15 (88%) 9 (60%) > 0.05
  Females 2 [30] 6 [31] > 0.05
  Average age at Diagnosis 3.6 years 3.1 years > 0.05
Clinical Data ENT 10 (59%) 12 (80%) > 0.05
  Respiratory 15 (88%) 11 (73%) > 0.05
  GI 2 [32] 2 [33] > 0.05
  Atopy 11 (65%) 9 (60%) > 0.05
  Family History 4 (24%) 3 (20%) > 0.05
Diagnosis IgAD 9 (53%) 7 (48%) > 0.05
  IgGD 12 (71%) 10 (68%) > 0.05
  IgMD 2 [34] 3 (20%) > 0.05
Treatment Antibiotics 4 (24%) 8 (53%) > 0.05
  IVIg 2 [35] 1 [36] > 0.05
Outcome No Infections 14 (83%) 13 (87%) > 0.05
Follow-up (years) Age at last follow-up 7.1 5.5 > 0.05
  Length of follow-up 3.5 2.5 > 0.05
  1. THGI – Transient Hypogammglobulinemia of Childhood
  2. Non Transient – Hypogammaglobulinemic patients who did not correct during follow-up
  3. IgAD – IgA 2SD bellow age specific norms
  4. IgGD – One or more IgG isotype 2SD bellow age specific norms
  5. IgMD – IgM 2SD bellow age specific norms
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