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Table 2 Mean changes in metabolic parameters between baseline and endpoint in women treated with placebo or paroxetine

From: Quality of life and metabolic status in mildly depressed women with type 2 diabetes treated with paroxetine: A single-blind randomised placebo controlled trial

  Placebo (n = 6) Paroxetine (n = 7) 95% confidence interval of difference between groups p*
  Mean SD Mean SD   
Body weight (kg) -0.83 0.98 -0.71 2.29 -2.30 to 2.06 0.60
Body mass index (kg/m2) -0.31 0.38 -0.26 0.88 -0.88 to 0.79 0.51
Blood glucose (mmol/l) -0.78 0.58 -1.47 2.52 -1.65 to 3.03 0.72
HbA1c % -0.07 0.33 -0.44 0.37 -0.05 to 0.80 0.08
S-cholesterol (mmol/l) -0.37 0.72 -0.16 0.62 -1.05 to 0.63 0.47
HDL-cholesterol (mmol/l) -0.07 0.10 0.01 0.13 -0.22 to 0.07 0.28
LDL-cholesterol (mmol/l) -0.38 0.65 -0.31 0.51 -0.80 to 0.68 0.57
S-triglycerides (mmol/l) 0.16 0.28 0.31 0.77 -0.87 to 0.58 0.72
Free fatty acids (mmol/l) -0.13 0.48 -0.29 0.41 -0.40 to 0.71 0.56
Sex hormone binding globulin (nmol/l) -9.33 15.67 20.29 20.57 -51.81 to -7.43 0.01
S-leptin (ng/ml) -3.75 6.73 -3.54 5.99 -8.12 to 7.70 0.89
S-cortisol (nmol/l) 104.83 151.05 -42.29 133.73 -30.17 to 324.41 0.06
Energy expenditure (kcal/d) -33.33 157.69 28.57 177.05 -266.35 to 142.54 0.57
  1. *Mann-Whitney U-test