Table 5 Effect in placebo-controlled and active controlled trials. Most commonly used dose in the trials.
Weighed mean change from baseline | ||||
|---|---|---|---|---|
Statin and dose | Number of patients | Initial [TC] | Absolute | Percent |
Placebo controlled trials | ||||
Atorvastatin 10 mg | 835 | 7.1 | -1.9 | -27 |
Cerivastatin 0.4 mg | No data | |||
Fluvastatin 40 mg | 58 | 7 | -1.2 | -18 |
Lovastatin 40 mg | 3436 | 6.7 | -1.5 | -23 |
Pravastatin 40 mg | 5807 | 6.3 | -1.3 | -20 |
Rosuvastatin 5 mg | 129 | 7.2 | -2.0 | -28 |
Rosuvastatin 10 mg | 130 | 7.0 | -2.1 | -30 |
Simvastatin 40 mg | 10516 | 5.6 | -1.5 | -26 |
Active controlled trials | ||||
Atorvastatin 10 mg | 272 | 7.3 | -2.1 | -29 |
Cerivastatin 0.4 mg | 195 | 7.2 | -1.7 | -23 |
Fluvastatin 40 mg | 144 | 8.1 | -1.4 | -17 |
Lovastatin 40 mg | 307 | 7.8 | -1.6 | -21 |
Pravastatin 40 mg | 640 | 7.2 | -1.6 | -22 |
Rosuvastatin 5 mg | 381 | 7.3 | -2.2 | -30 |
Rosuvastatin 10 mg | 365 | 7 | -2.4 | -34 |
Simvastatin 40 mg | No data | |||