Quality of life and health care consumption in primary care patients with elevated serum calcium concentrations in - a prospective, case control, study

Table 1 Characteristics of patients with elevated and normal calcium concentrations 1995–2000 and 2008–2010, men and women, at Tibro Health Care Centre, Sweden

	Patients with elevated calcium concentrations						Patients with normal calcium concentrations						Comparison between the groups
	*Total*		*Men*		*Women*		*Total*		*Men*		*Women*		*Total* p -value	*Men* p -value	*Women* p -value
Variables	Mean	Percentile	Mean	Percentile	Mean	Percentile	Mean	Percentile	Mean	Percentile	Mean	Percentile
Data from register 1995–2000
Number	127		28		99		254		56		198
Age, January 1st 1995	61.4	36.6- 80.0	55.6	31.8- 77.0	63.0	38.8- 80.2	61.3	36.3- 80.0	55.5	39.0- 80.3	62.9	31.0- 77.0	n.s	n.s	n.s
Age, range	18–94		18–82		18–94		18–91		18–82		18–91
S- Calcium¹	2.66	2.56- 2.78	2.72	2.57- 2.88	2.64	2.56- 2.78	2.33	2.21- 2.43	2.31	2.19- 2.42	2.33	2.21- 2.44	<0.001	<0.001	<0.001
Data from clinical investigation 2008–2010
Number	63		12		51		133		33		100
Age, January 1st 2011	71.4	49.4- 89.0	67.7	49.2- 80.0	72.3	52.0- 89.0	70.0	45.2- 88.0	66.8	45.2- 84.4	71.0	45.8- 90.0	n.s	n.s	n.s
Age, range	31–97		45–82		31–97		30–99		31–99		30–97
P- Calcium²	2.42	2.26- 2.59	2.39	2.18- 2.55	2.43	2.27- 2.64	2.35	2.22- 2.47	2.32	2.21- 2.42	2.36	2.23- 2.48	<0.001	0.085	0.003
Ionised Calcium³	1.29	1.22- 1.40	1.28	1.24- 1.31	1.29	1.22- 1.44	1.23	1.18- 1.27	1.22	1.16- 1.26	1.23	1.18- 1.28	<0.001	<0.001	<0.001
Parathyroid hormone⁴	68	20- 118	60	14- 136	69	21- 113	58	26- 107	57	22- 104	59	28- 113	n.s	n.s	n.s

Notes: Data are means (SD), n.s = not significant, Age in years. Reference range ¹Serum Calcium analysed in whole blood (mmol/L) 2.15–2.55 (mmol/L), ²Plasma Calcium (mmol/L) 2.15–2.50, ³Ionised Calcium (mmol/L) 1.15–1.35, ⁴Parathyroid hormone (ng/L) 15–65.

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