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Table 1 Patient characteristics and findings in primary care patients with acute cough categorized by CRP 1 testing

From: Usefulness of C-reactive protein testing in acute cough/respiratory tract infection: an open cluster-randomized clinical trial with C-reactive protein testing in the intervention group

 

Intervention group, CRP tested (n = 101)

Control group, CRP not tested (n = 78)

P

 

n

(%)

n

(%)

 

Male

29

(28)

20

(26)

0.7

Current smokers

28

(27)

16

(21)

0.3

Pre-existing illness:

     

Pulmonary diseases

15

(15)

14

(18)

0.7

Heart diseases

17

(17)

3

(4)

0.007

Diabetes

5

(5)

3

(4)

1.0

Any comorbidity

55

(54)

39

(50)

0.6

Symptoms2:

     

Cough

60

(59)

48

(62)

0.9

Sputum

20

(20)

21

(27)

0.3

Discoloured sputum

56

(57)

49

(63)

0.4

Shortness of breath

9

(9)

11

(14)

0.3

Wheeze (reported)

9

(9)

17

(22)

0.02

Coryza

19

(19)

9

(12)

0.2

Fever (history of)

31

(31)

26

(33)

0.7

Chest pain

5

(5)

5

(6)

0.7

Muscle aches

13

(13)

2

(3)

0.01

Headache

19

(19)

4

(5)

0.07

Disturbed sleep

10

(10)

4

(5)

0.3

Feeling unwell

47

(46)

15

(19)

0.0001

Interference with daily activities

44

(43)

15

(19)

0.0007

Symptom severity3

44

 

43

 

0.4

 

(27–63)

 

(29–69)

  

Findings:

     

Diminished breath sounds

29

(29)

30

(38)

0.2

Wheezes

21

(21)

19

(24)

0.6

Crackles

3

(3)

2

(3)

1.0

Rhonchi

7

(7)

3

(4)

0.5

Any abnormal lung sound

60

(59)

54

(69)

0.2

Temperature ≥ 37.2°C

51

(50)

49

(63)

0.1

CRP ≥ 20 and < 50 mg/L

13

(13)

   

CRP ≥ 50 mg/L

7

(7)

   

Perceived patient preference for antibiotics3

10

(10)

18

(23)

0.02

  1. 1CRP = C-reactive protein.
  2. 2Reported by patient to be a moderate or severe problem.
  3. 3Symptom severity scores calculated using the scores for 13 symptoms that were summed, and median, minimum and maximum values (in brackets) calculated.
  4. 4The general practitioner agreed that the patient wanted her/him to prescribe antibiotics.