Criteria | Explanation |
---|---|
Febrile syndrome | Fever of unknown origin and temperature ≥ 38 °C for ≥ 14 days |
Unintentional weight loss | Unaccounted for loss of ≥10% of body weight, anorexia, asthenia for ≥ 42 days |
Anemia | Hemoglobin level < 9 g/L, with or without symptoms |
Chronic diarrhea | Loose stools for ≥ 28 days |
Adenopathies and/or palpable masses | - |
Unexplained severe abdominal pain | - |
Rectorrhagia | - |
Jaundice | - |
Severe constipation (recent onset) | - |
Lung and/or pleural abnormalities | Mainly suggestive of neoplasm. After exclusion of obvious causes including community-acquired pneumonia or residual lesions |
Unexplained dyspnea | - |
Ascites and/or anasarca | - |
Dysphagia | - |
Arthritis | Degenerative osteoarthritis excluded |
Bone pain with suspicion of bone malignancy | - |
Splenomegaly and/or hepatomegaly | No known liver or hematological disease (e.g., chronic myelogenous leukemia) |
Hemogram abnormalities suggestive of primary hematological disorder | - |
Neurologic disorders (central, spinal and peripheral nervous system) | Cerebrovascular disease, delirium, dementia, movement and sleep disorders, dizziness, vertigo, and neuropathic pain excluded. |
Includes Horner’s syndrome | |
Monoclonal paraprotein band with or without suspicion of multiple myeloma | - |