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Table 4 Diagnostic characteristics of exercise test outcome (positive/non-conclusive tests)

From: Diagnostic characteristics and prognoses of primary-care patients referred for clinical exercise testing: a prospective observational study

Characteristic

Exertional chest pain*

Pathologic ST-T segment**

Angina diagnosis according to the patient’s opinion†

(95% CI)

(95% CI)

(95% CI)

Number of patients with characteristic

134

42

80

Sensitivity

69.1% (62.3-75.2)

21.3% (16.2-27.6)

43.2% (36.3-50.5)

Specificity

58.0% (54.1-61.8)

90.5% (88.0-92.5)

79.1% (75.6-82.1)

Positive predictive value

33.2% (30.4-36.2)

40.4% (32.2-49.2)

38.4% (33.2-43.9)

Negative predictive value

86.1% (83.3-88.6)

79.2% (77.9-80.4)

82.2% (80.2-84.0)

Likelihood ratio for positive test

1.7 (1.4- 1.9)

2.3 (1.6-3.2)

2.1 (1.7-2.6)

Likelihood ratio for negative test

0.5 (0.4-0.7)

0.9 (0.8-0.9)

0.7 (0.6-0.8)

Pre-test probability of having a positive/non-conclusive exercise test

23.2%

23.2%

23.2%

Net gain after positive result

10.0% (7.2-13.3)

17.2% (9.0-26.0)

15.2% (10.0-20.7)

Number of patients with characteristic per positive/non-conclusive exercise test

3.0

2.5

2.6

  1. *Chest pain when walking uphill or in a hurry. **Pathologic ST-T segment on resting electrocardiogram. †Patient’s opinion of angina diagnosis: yes or no. CI: confidence interval. Positive exercise test: angina symptoms and ST-segment depression >0.1 mV during the test. Non-conclusive test: angina or ST depression. Negative test: neither angina nor ST depression.