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Table 2 Total number of contacts with general practice in 2008 for patients with ten prevalent chronic diseases grouped by their number of chronic diseases (out of 27 chronic diseases): means and 95% confidence intervals are presented, adjusted for sex, age, and clustering of patients within general practices 1

From: Multimorbidity of chronic diseases and health care utilization in general practice

  Number of patients Single chronic disease Number of additional chronic diseases P-value for linear trend
  1 2 3 ≥4
Diabetes 4806 14.4 (13.3 15.6) 18.5 (16.9 20.3) 23.3 (20.5 26.5) 26.6 (24.2 29.3) 32.3 (28.8 36.3) <0.001
Coronary heart disease 3341 11.8 (10.7 13.0) 17.1 (15.4 18.9) 21.8 (19.8 24.1) 25.7 (23.3 28.3) 31.7 (27.7 36.2) <0.001
Osteoarthritis 3394 10.8 (9.9 11.8) 16.2 (14.9 17.7) 20.7 (19.1 22.6) 23.4 (21.5 25.4) 28.4 (21.5 31.7) <0.001
COPD 2466 13.6 (12.5 14.9) 17.2 (15.7 18.8) 22.4 (20.1 25.0) 25.3 (23.5 27.3) 32.1 (28.5 36.1) <0.001
Chronic back- or neck disorder 2703 9.4 (8.7 10.3) 14.7 (13.4 16.2) 19.2 (17.3 21.4) 23.8 (21.3 26.6) 27.9 (24.3 31.9) <0.001
Cancer 2269 11.5 (10.6 12.4) 16.8 (15.2 18.5) 21.4 (18.6 24.5) 23.1 (19.9 26.9) 32.0 (28.1 36.5) <0.001
Stroke 1632 12.9 (11.8 14.2) 17.7 (16.1 19.4) 21.8 (19.5 24.4) 25.1 (22.6 28.0) 29.4 (26.4 32.8) <0.001
Depression 1693 12.7 (11.5 14.0) 17.7 (15.8 19.9) 23.2 (20.2 26.6) 26.8 (24.3 29.5) 32.3 (28.4 36.8) <0.001
Heart failure 1471 16.7 (14.8 18.8) 22.0 (19.9 24.3) 26.6 (24.3 29.2) 30.0 (27.3 32.9) 36.7 (33.2 40.5) <0.001
Anxiety disorder 675 12.8 (10.9 15.0) 17.6 (15.2 20.4) 22.1 (19.1 25.5) 25.6 (21.8 30.0)   <0.001
  1. 1Means and 95% confidence intervals not shown when the number of patients with a chronic disease and a number of additional chronic diseases is lower than 50.