Table 5 Predictors of ICS/LABA prescribing as determined by bivariate logistic regression according to lung function in 376 patients aged ≥40 years diagnosed with an obstructive lung disease in primary care according to whether COPD is indicated by spirometry (FEV 1 /FVC <0.7; n = 149) or not (n = 227)
From: Predictors of ICS/LABA prescribing in COPD patients: a study from general practice
FEV1/FVC <0.7 | FEV1/FVC ≥0.7 | |||||
|---|---|---|---|---|---|---|
OR | 95% CI | P-value | OR | 95% CI | P-value | |
Age 65+ years | 0.8 | 0.4–1.6 | 0.6 | 1.0 | 0.6–1.8 | 0.9 |
Male | 0.6 | 0.4–1.3 | 0.7 | 1.0 | 0.6–1.8 | 0.9 |
Never smoker | 1 | 1 | ||||
Current smoker | 0.3 | 0.1–1.1 | 0.06 | 0.7 | 0.4–1.4 | 0.3 |
Previous smoker | 0.5 | 0.1–1.4 | 0.5 | 0.7 | 0.4–1.3 | 0.3 |
Diagnosis (by GP) | ||||||
Asthma | 3.1 | 1.6–6.2 | 0.001 | 6.3 | 1.4–28.4 | 0.02 |
COPD | 0.5 | 0.2–1.2 | 0.1 | 0.6 | 0.3–1.2 | 0.1 |
Cardiovascular disease | 0.4 | 0.2–0.8 | 0.01 | 1.2 | 0.7–2.2 | 0.6 |
Allergic illness | 1.5 | 0.8–3.2 | 0.2 | 1.4 | 0.8–2.4 | 0.2 |
Exacerbation in the previous year | 2.0 | 1.0–4.1 | 0.04 | 2.3 | 1.9–4.5 | 0.01 |
CCQ mean scorea | ||||||
<1 | 1 | 1 | ||||
1–2 | 1.8 | 0.7–4.5 | 0.2 | 1.3 | 0.7–2.6 | 0.4 |
≥2 | 2.0 | 0.8–5.0 | 0.1 | 2.2 | 1.1–4.3 | 0.03 |
FEV1% predicted | ||||||
≥50% | 1 | 1 | ||||
<50% | 1.6 | 0.8–3.3 | 0.2 | 2.9 | 0.6–15.5 | 0.2 |