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Table 3 Comparison between general characteristics of control group and intervention group

From: Effectiveness of a drug dosing service provided by community pharmacists in polymedicated elderly patients with renal impairment — a comparative study

 

Control group

Intervention group

P

Sex

 

%(n)

  

0.75a

 

Women

 

68.7 (121)

59.2(103)

 
 

Men

 

31.3(55)

40.8(71)

 
 

Overall

 

100(176)

100.0(174)

 

Mean ± SD

   

Age (years)

83.3 ± 6.9

80.8 ± 7.3

0.001b

Weight (kg)

65.5 ± 12.1

66.8 ± 12.0

0.335b

Height (m)

1.6 ± 0.1

1.6 ± 0.1

0.069b

BMI (Kg/m2)

26.1 ± 4.0

26.3 ± 3.8

0.721b

SBP (mm Hg)

130.7 ± 17.3

134.7 ± 18.7

0.060b

DBP (mm Hg)

71.5 ± 11.3

75.0 ± 12.3

0.012b

Creatinine (mg/dl)

1.1 ± 0.4

1.2 ± 0.8

0.052b

Body surface (m2)

1.7 ± 0.2

1.7 ± 0.2

0.162b

GFR (ml/min/1.73 m2)

61.7 ± 16.5

60.7 ± 17.0

0.572b

CrCl (ml/min)

45.0 ± 12.1

45. + ±13.0

0.525b

CrCl-BS (ml/min/1.73 m2)

46.3 ± 11.6

47.1 ± 12.6

0.550b

Total number of drugs per patient

7.3 ± 2.9

6.3 ± 3.2

0.003b

Drugs with restriction in RI per patient

4.0 ± 2.0

3.5 ± 2.1

0.069b

Number of DRP per patient

0.7 ± 1.0

0.5 ± 1.0

0.164b

Prevalence of DI (%)

17.5 ± 28.2

15.5 ± 29.1

0.514b

Comorbidity %(n)

   

 Hypertension

72.2(127)

69.5(121)

0.639a

 T2DM

23.9(42)

11.5(20)

0.003a

 Dyslipidemia

39.8(70)

37.4(65)

0.662a

 Hyper/Hypo Thyroidism

5.7(10)

6.3(11)

0.826a

 CVD

30.7(54)

23.6(41)

0.150a

 CKD

10.2(18)

8.0(14)

0.579a

  1. Abbreviations: BMI Body Mass Index, SBP Systolic Blood Pressure, DBP, Diastolic Blood Pressure, T2DM Type 2 Diabetes Mellitus, CVD Cardiovascular Disease, CKD Chronic Kidney Disease, GFR Rate of Glomerular filtration, CrCl Creatinine Clearance, CrCl-BS Creatinine Clearace adjusted to body surface, RI renal impairment, DRP Drug-related problem, DI Dosing inadequacy, Drugs with restrictions (dose adjustment needed in case of renal impairment (RI)) per patient [2022], SD Standard deviation.
  2. aχ2Test.
  3. b T Student test for independent groups.