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Table 3 Comparison between general characteristics of control group and intervention group

From: Effectiveness of a drug dosing service provided by community pharmacists in polymedicated elderly patients with renal impairment — a comparative study

  Control group Intervention group P
Sex   %(n)    0.75a
  Women   68.7 (121) 59.2(103)  
  Men   31.3(55) 40.8(71)  
  Overall   100(176) 100.0(174)  
Mean ± SD    
Age (years) 83.3 ± 6.9 80.8 ± 7.3 0.001b
Weight (kg) 65.5 ± 12.1 66.8 ± 12.0 0.335b
Height (m) 1.6 ± 0.1 1.6 ± 0.1 0.069b
BMI (Kg/m2) 26.1 ± 4.0 26.3 ± 3.8 0.721b
SBP (mm Hg) 130.7 ± 17.3 134.7 ± 18.7 0.060b
DBP (mm Hg) 71.5 ± 11.3 75.0 ± 12.3 0.012b
Creatinine (mg/dl) 1.1 ± 0.4 1.2 ± 0.8 0.052b
Body surface (m2) 1.7 ± 0.2 1.7 ± 0.2 0.162b
GFR (ml/min/1.73 m2) 61.7 ± 16.5 60.7 ± 17.0 0.572b
CrCl (ml/min) 45.0 ± 12.1 45. + ±13.0 0.525b
CrCl-BS (ml/min/1.73 m2) 46.3 ± 11.6 47.1 ± 12.6 0.550b
Total number of drugs per patient 7.3 ± 2.9 6.3 ± 3.2 0.003b
Drugs with restriction in RI per patient 4.0 ± 2.0 3.5 ± 2.1 0.069b
Number of DRP per patient 0.7 ± 1.0 0.5 ± 1.0 0.164b
Prevalence of DI (%) 17.5 ± 28.2 15.5 ± 29.1 0.514b
Comorbidity %(n)    
 Hypertension 72.2(127) 69.5(121) 0.639a
 T2DM 23.9(42) 11.5(20) 0.003a
 Dyslipidemia 39.8(70) 37.4(65) 0.662a
 Hyper/Hypo Thyroidism 5.7(10) 6.3(11) 0.826a
 CVD 30.7(54) 23.6(41) 0.150a
 CKD 10.2(18) 8.0(14) 0.579a
  1. Abbreviations: BMI Body Mass Index, SBP Systolic Blood Pressure, DBP, Diastolic Blood Pressure, T2DM Type 2 Diabetes Mellitus, CVD Cardiovascular Disease, CKD Chronic Kidney Disease, GFR Rate of Glomerular filtration, CrCl Creatinine Clearance, CrCl-BS Creatinine Clearace adjusted to body surface, RI renal impairment, DRP Drug-related problem, DI Dosing inadequacy, Drugs with restrictions (dose adjustment needed in case of renal impairment (RI)) per patient [2022], SD Standard deviation.
  2. aχ2Test.
  3. b T Student test for independent groups.