|
Mean ± SD
|
Women(173)
|
Men(90)
|
Overall(263)
|
|---|
|
Age (years)
|
83.1 ± 7.2
|
82.6 ± 6.9
|
82.9 ± 7.1
|
|
Weight (kg)
|
62.9 ± 11.6
|
73.9 ± 10.1
|
69.8 ± 12.2
|
|
Height (m)
|
1.5 ± 0.1
|
1.6 ± 0.1
|
1.6 ± 0.1
|
|
BMI (Kg/m2)
|
26.4 ± 4.1
|
27.0 ± 3.2
|
26.6 ± 3.9
|
|
SBP (mm Hg)
|
130.6 ± 17.5
|
130.9 ± 17.7
|
130.7 ± 17.5
|
|
DBP (mm Hg)
|
70.8 ± 11.1
|
71.7 ± 11.3
|
71.1 ± 11.2
|
|
Creatinine (mg/dl)
|
1.1 ± 0.9
|
1.30 ± 0.4
|
1.2 ± 0.8
|
|
Body surface (m2)
|
1.6 ± 0.2
|
1.8 ± 0.1
|
1.7 ± 0.2
|
|
GFR (ml/min/1.73 m2)
|
61.0 ± 16.9
|
59.2 ± 16.1
|
60.4 ± 16.7
|
|
CrCl (ml/min)
|
43.0 ± 11.7
|
47.5 ± 12.9
|
45.2 ± 12.2
|
|
CrCl-BS (ml/min/1.73 m2)
|
46.7 ± 11.6
|
44.5 ± 10.9
|
45.0 ± 11.4
|
|
Total number drugs patient
|
7.3 ± 3.0
|
7.2 ± 2.9
|
7.3 ± 2.9
|
|
Drugs with restrictions per patient
|
4.0 ± 1.9
|
4.0 ± 2.9
|
4.0 ± 2.0
|
|
Number of DRP per patient
|
0.7 ± 1.1
|
0.6 ± 1.1
|
0.7 ± 1.1
|
|
Prevalence of DI (%)
|
18.3 ± 28.9
|
15.8 ± 28.4
|
17.5 ± 28.2
|
|
Population with DRP %(n)
|
35.6(32)
|
38.2(66)
|
37.3(98)
|
|
Comorbidity %(n)
| | | |
|
Hypertension
|
71.7%(124)
|
67.8%(61)
|
70.3%(185)
|
|
T2DM
|
19.7%(34)
|
24.4%(22)
|
21.3%(56)
|
|
Dyslipidemia
|
37.0%(64)
|
36.7%(33)
|
36.9%(97)
|
|
Hyper/Hypo Thy
|
8.1(14)
|
1.1%(1)
|
5.7%(15)
|
|
CVD
|
26.6(46)
|
31.1%(28)
|
28.1%(74)
|
- Abbreviations: BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, T2DM Type 2 Diabetes Mellitus, CVD Cardiovascular Disease, THY Thyroidsm, GFR Rate of Glomerular filtration, CrCl Creatinine Clearance, CrCl-BS Creatinine Clearance adjusted to body surface, RI renal impairment, DRP Drug-related problem, DI Dosing inadequacy, Drugs with restrictions (dose adjustment needed in case of renal impairment (RI)) per patient [20–22], SD Standard deviation.
