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Table 3 Factors associated with achievement of BP targets in people on antihypertensive medication

From: Suboptimal blood pressure control in chronic kidney disease stage 3: baseline data from a cohort study in primary care

  

Univariate odds ratios of achieving NICE BP targets

Multivariable odds ratios of achieving NICE BP target ∞

Univariate odds ratios of achieving KDOQI BP targets

Multivariable odds ratios of achieving KDOQI BP target †

Univariate odds ratios of achieving KDIGO BP targets

Multivariable odds ratios of achieving KDIGO BP target ∞

  

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Sex (compared to female)

Male

0.91 (0.73,1.12)

0.359

0.88 (0.71,1.10)

0.260

0.80 (0.64,1.00)

0.050

0.76 (0.60,0.96)

0.023

0.75 (0.61,0.93)

0.009

0.93 (0.74,1.18)

0.56

Age (compared to <60 age group)

60-69

0.60 (0.36,1.03)

<0.001

0.43 (0.26,0.71)

<0.001

0.73 (0.46, 1.18)

0.155

0.66 (0.41,1.08)

0.002

0.66 (0.39,1.12)

0.001

0.51 (0.29,0.89)

<0.001

 

70-79

0.43 (0.26,0.71)

 

0.27 (0.17,0.43)

 

0.64 (0.41,1.01)

 

0.49 (0.31,0.79)

 

0.52 (0.32,0.87)

 

0.34 (0.20,0.58)

 
 

80+

0.35 (0.21,0.59)

 

0.21 (0.13,0.35)

 

0.60 (0.38, 0.97)

 

0.43 (0.26,0.72)

 

0.41 (0.24,0.68)

 

0.27 (0.15,0.48)

 

Diabetes (compared to people without diabetes)

People with diabetes

0.36 (0.28,0.47)

<0.001

0.32 (0.25,0.43)

<0.001

1.12 (0.86,1.17)

0.410

1.08 (0.81,1.43)

0.601

0.97 (0.74,1.26)

0.796

1.14 (0.85,1.53)

0.38

Albuminuria (compared to no albuminuria)

People with albuminuria

0.54 (0.41,0.72)

<0.001

0.56 (0.42,0.74)

0.001

0.70 (0.52, 0.95)

0.021

0.65 (0.47,0.90)

0.009

0.70 (0.52,0.95)

0.021

0.21 (0.16,0.30)

<0.001

History of CVD (compared to people with no CVD)

People with CVD

1.41 (1.13,1.76)

0.002

1.87 (1.49,2.35)

<0.001

1.66 (1.33,2.07)

<0.001

1.89 (1.49,2.39)

<0.001

1.42 (1.14,1.77)

0.002

1.83 (1.43,2.34)

<0.001

eGFR (compared to 45–59)

60+

1.03 (0.81,1.31)

0.001

0.84 (0.65, 1.09)

0.088

0.78 (0.62,1.00)

0.145

-

-

0.97 (0.74,1.28)

0.004

0.83 (0.62,1.11)

0.27

 

<45

0.66 (0.52, 0.83)

 

0.77 (0.60, 0.99)

 

0.92 (0.72, 1.17)

   

0.66 (0.52,0.85)

 

0.83 (0.64, 1.09)

 
  1. ∞ Model adjusted for age, sex, albuminuria, diabetes, CVD, and eGFR.
  2. † Model adjusted for age, sex, albuminuria, diabetes, and CVD.
  3. Abbreviations:
  4. BP blood pressure.
  5. RAASi renin-angiotensin aldosterone system inhibitors.
  6. NICE National Institute for Health and Clinical Excellence.
  7. KDOQI National Kidney Foundation Kidney Disease Outcome Quality Initiative.
  8. CVD cardiovascular disease.
  9. eGFR estimated Glomerular Filtration Rate.