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Table 3 Prevalence and test performance of the single item screener using the “depressive mood” definition of the 9-item Patient Health Questionnaire (PHQ-9) as reference standard (95% confidence interval)

From: Diagnostic utility of a one-item question to screen for depressive disorders: results from the KORA F3 study

Age group Prevalence Sensitivity Specifity ROC area LR+ LR- PPV NPV
34-44 20 (17–23.3) 37.5 (29.1-46.5) 96.5 (94.5-97.9) .67 (.627-.713) 10.6 (6.42-17.7) .648 (.556-.742) 72.7 (60.4-83) 86 (82.9-88.8)
45-54 25 (22–27.9) 46.1 (38.7-53.7) 95.5 (93.4-97) .708 (.67-.745) 10.2 (6.72-15.4) .565 (.493-.647) 76.9 (67.8-84.4) 84.4 (81.3-87.2)
55-64 31 (28–34.9) 45.8 (39.4-52.4) 93.7 (91.3-95.6) .698 (.664-.731) 7.26 (5.08-10.4) .578 (.514-.651) 76.9 (69.1-83.6) 79 (75.6-82.2)
65-74 32 (28–35.6) 47.9 (41–54.8) 92.7 (89.9-94.9) .703 .667-.739) 6.54 (4.58-9.35) .562 (.493-.642) 75.4 (67.2-82.4) 79.2 (75.4-82.6)
75-85 34 (29–39.4) 52.5 (43.2-61.6) 91 (86.6-94.3) .717 (.669-.765) 5.82 3.74-9.05) .523 (.432-.632) 75.3 (64.7-84) 78.5 (73.1-83.3)
Female 34 (32–36.3) 48.8 (44.6-53.1) 92.3 (90.5-93.8) .705 (.683-.728) 6.31 (5.05-7.89) .555 (.51-.603) 76.4 (71.6-80.8) 77.8 (75.4-80.1)
Male 22 (20–23.8) 41.5 (36.1-47) 96.1 (94.8-97.1) .688 (.661-.715 10.6 (7.76-14.4) .809 (.555-.667) 74.5 (67.5-80.6) 85.6 (83.6-87.5)
Total 28 (26–29.6) 46.1 (42.8-49.4) 94.3 (93.2-95.2) .702 (.685-.719) 8.04 (6.71-9.64) .572 (.538-.608) 75.7 (71.9-79.3) 81.8 (80.3-83.3)
  1. ROC: receiver operating characteristic; LR+: positive likelihood ratio; LR-: negative likelihood ratio; PPV: positive predictive value; NPV: negative predictive value.