Pre IBS (n = 7728) | Post IBS (n = 7665) | Pre AP (n = 39974) | Post AP (n = 37851) | Pre IBD (n = 1336) | Post IBD (n = 1382) | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Medications† | n | % | n | % | n | % | n | % | n | % | n | % |
NICE medications | 2395 | 31.0 | 4099 | 53.5 | 8560 | 21.4 | 13871 | 36.6 | 389 | 29.1 | 442 | 32.0 |
Bulking laxatives | 288 | 3.7 | 629 | 8.2 | 754 | 1.9 | 1561 | 4.1 | 40 | 3.0 | 50 | 3.6 |
Stimulant laxatives | 204 | 2.6 | 247 | 3.2 | 1106 | 2.8 | 1688 | 4.5 | 36 | 2.7 | 59 | 4.3 |
Faecal softeners | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
Osmotic laxatives | 216 | 2.8 | 289 | 3.8 | 845 | 2.1 | 1550 | 4.1 | 27 | 2.0 | 50 | 3.6 |
Antimotility drugs | 246 | 3.2 | 429 | 5.6 | 727 | 1.8 | 979 | 2.6 | 132 | 9.9 | 169 | 12.2 |
Antispasmodic drugs | 1328 | 17.2 | 3397 | 44.3 | 1890 | 4.7 | 7035 | 18.6 | 157 | 11.8 | 149 | 10.8 |
Tricyclic antidepressants | 397 | 5.1 | 553 | 7.2 | 1924 | 4.8 | 2221 | 5.9 | 66 | 4.9 | 78 | 5.6 |
SSRI | 808 | 10.5 | 957 | 12.5 | 3530 | 8.8 | 3955 | 10.4 | 101 | 7.6 | 129 | 9.3 |
Other antidepressants | 124 | 1.6 | 147 | 1.9 | 554 | 1.4 | 660 | 1.7 | 12 | 0.9 | 15 | 1.1 |