Figure 1From: Challenges in diagnostic accuracy studies in primary care: the fecal calprotectin example Flow chart of the DOK study. The PCP or pediatric gastroenterologist selects eligible children. At baseline inclusion, exclusion criteria and red flag symptoms are determined. The parents and child ≥10 years complete two questionnaires, i.e. a Questionnaire on Pediatric Gastrointestinal Symptoms (QPGS) and a symptoms questionnaire, in addition feces (parasites and colon pathogens) are obtained. Children meeting 1 ≥ red flag symptoms are evaluated for eligibility for endoscopy by a pediatric gastroenterologist. Children without red flag symptoms receive a 1-year follow-up. The arrows indicate that the PCP can refer a child during follow-up for endoscopic evaluation and the children who are not eligible for endoscopy receive a follow-up. After 1 year, information about diagnosis and clinical symptoms is collected based on the two above-mentioned questionnaires.Back to article page